LbrM.27.1480

hypothetical protein, unknown function
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_200140 OG7: OG7_0052146 75 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 75 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.09.0820
ubiquitin ligase, putative
— OG7
LbrM.05.0180
dihydrolipoamide branched chain transacylase,
— OG7
LbrM.12.0270
cysteinyl-tRNA synthetase, putative
— OG7
LbrM.33.0340 ⚠
heat shock protein 83, heat shock protein 83-
— OG7
LbrM.18.0370
ATP12 chaperone protein, putative
— OG7
LbrM.25.1890
Leucine Rich repeats (2 copies), putative
— OG7
LbrM.15.1160 ⚠
inositol/phosphatidylinositol phosphatase, pu
— OG7
LbrM.10.0290
exonuclease, putative
— OG7
LbrM.24.0010 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— OG7
LbrM.08.0470
WD domain, G-beta repeat, putative
— OG7
LbrM.33.0330 ⚠
heat shock protein 83-1
— OG7
LbrM.20.1490
Zeta toxin, putative
— OG7
LbrM.29.0780 ⚠
heat shock protein 90, putative
— OG7
LbrM.23.0300
pteridine reductase 1
— OG7
LbrM.19.1320
phenylalanyl-tRNA synthetase, putative
— OG7
LbrM.33.0830
ATP synthase F1 subunit gamma protein
— OG7
LbrM.20.4500 ⚠
developmentally regulated phosphoprotein-like
— OG7
LbrM.29.0030
transcription factor-like protein
— OG7
LbrM.33.0350 ⚠
heat shock protein 83-1
— OG7
LbrM.24.0840 ⚠
inositol polyphosphate phosphatase, putative
— OG7
LbrM.35.7120 ⚠
beta adaptin, putative
— OG7
LbrM.11.0790 ⚠
adaptin-related protein-like protein
— OG7
LbrM.35.5510 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
LbrM.24.2100
tubulin folding cofactor D, putative
— OG7
LbrM.26.1830 ⚠
hypothetical protein, conserved
— OG7
LbrM.10.1320 ⚠
hypothetical protein, conserved
— OG7
LbrM.15.0320 ⚠
ribonucleoprotein p18, mitochondrial precurso
— OG7
LbrM.15.0310 ⚠
ribonucleoprotein p18, mitochondrial precurso
— OG7
LbrM.20.3720
GRIP domain containing protein, putative
— OG7
LbrM.33.2670 ⚠
heat shock protein, putative
— OG7
LbrM.32.0280
Histone chaperone Rttp106-like, putative
— OG7
LbrM.08.0230 ⚠
ubiquitin-activating enzyme-like protein (fra
— OG7
LbrM.23.0120
GDP-mannose pyrophosphorylase
— OG7
LbrM.34.4210 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.1330
threonyl-tRNA synthetase, putative
— OG7
LbrM.33.2190
ribosome assembly protein RRB1, putative
— OG7
LbrM.01.0690 ⚠
ubiquitin activating enzyme, putative
— OG7
LbrM.35.2630
serine peptidase, Clan SC, Family S9B
— OG7
LbrM.07.0840 ⚠
6-phosphofructo-2-kinase-like protein
— OG7
LbrM.32.3160 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
LbrM.27.1390 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LbrM.20.1840 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LbrM.34.2360 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
LbrM.24.1970
WD domain, G-beta repeat/PFU (PLAA family ubi
— OG7
LbrM.20.3910
nucleolar protein family a, putative
— OG7
LbrM.35.6680 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LbrM.23.0650 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LbrM.34.2290 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LbrM.34.0690
vacuolar ATP synthase subunit d, putative
— OG7
LbrM.35.0220 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.