LbrM.05.0180

dihydrolipoamide branched chain transacylase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101891 OG7: OG7_0001831 101 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 101 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.20.3910
nucleolar protein family a, putative
— Both
LbrM.35.7120 ⚠
beta adaptin, putative
— Both
LbrM.11.0400 ⚠
aminopeptidase, putative, metallo-peptidase,
— Both
LbrM.11.0410 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
LbrM.34.0820 ⚠
NADH-dependent fumarate reductase-like protei
— Both
LbrM.34.1110 ⚠
NADH-dependent fumarate reductase, putative
— Both
LbrM.34.1090 ⚠
NADH-dependent fumarate reductase, putative
— Both
LbrM.34.1100 ⚠
NADH-dependent fumarate reductase, putative
— Both
LbrM.35.2630
serine peptidase, Clan SC, Family S9B
— Both
LbrM.20.3720
GRIP domain containing protein, putative
— Both
LbrM.24.0010 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— Both
LbrM.32.0960
phenylalanyl-tRNA synthetase alpha chain, put
— Both
LbrM.19.1320
phenylalanyl-tRNA synthetase, putative
— Both
LbrM.34.1330
threonyl-tRNA synthetase, putative
— Both
LbrM.12.0270
cysteinyl-tRNA synthetase, putative
— Both
LbrM.23.1260
coronin, putative
— Both
LbrM.20.1860
hypothetical protein, conserved
— Both
LbrM.19.0570
C-terminal motor kinesin, putative
— OG6
LbrM.21.2070 ⚠
centromere/microtubule binding protein cbf5,
— Both
LbrM.21.1980 ⚠
centromere/microtubule binding protein cbf5,
— Both
LbrM.03.0240 ⚠
long chain fatty Acyl CoA synthetase, putativ
— Both
LbrM.01.0520 ⚠
fatty acyl CoA syntetase 1, putative
— Both
LbrM.01.0550 ⚠
long-chain-fatty-acid-CoA ligase, putative (f
— Both
LbrM.01.0540 ⚠
long-chain-fatty-acid-CoA ligase, putative
— Both
LbrM.33.0830
ATP synthase F1 subunit gamma protein
— Both
LbrM.29.0030
transcription factor-like protein
— Both
LbrM.20.1490
Zeta toxin, putative
— Both
LbrM.08.0230 ⚠
ubiquitin-activating enzyme-like protein (fra
— Both
LbrM.08.0470
WD domain, G-beta repeat, putative
— Both
LbrM.10.0290
exonuclease, putative
— Both
LbrM.30.0390
kinesin, putative
— OG6
LbrM.20.1840 ⚠
asparaginyl-tRNA synthetase, putative
— Both
LbrM.20.5380 ⚠
calpain-like cysteine peptidase, putative, cy
— OG6
LbrM.04.0490 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LbrM.20.5390 ⚠
calpain-like cysteine peptidase, putative, cy
— OG6
LbrM.20.5340 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LbrM.18.0370
ATP12 chaperone protein, putative
— Both
LbrM.33.2190
ribosome assembly protein RRB1, putative
— Both
LbrM.01.0080 ⚠
carboxylase, putative
— OG6
LbrM.31.3570 ⚠
methylcrotonoyl-coa carboxylase biotinylated
— Both
LbrM.34.3280
hypothetical protein, conserved
— Both
LbrM.26.0340 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
LbrM.23.0300
pteridine reductase 1
— Both
LbrM.32.3160 ⚠
cysteine peptidase, Clan CA, family C19, puta
— Both
LbrM.30.0880
hypothetical protein, conserved
— Both
LbrM.20.2170 ⚠
ruvB-like DNA helicase, putative
— Both
LbrM.33.0350 ⚠
heat shock protein 83-1
— +2 more Both
LbrM.29.0780 ⚠
heat shock protein 90, putative
— +2 more Both
LbrM.33.0340 ⚠
heat shock protein 83, heat shock protein 83-
— +2 more Both
LbrM.33.0330 ⚠
heat shock protein 83-1
— +2 more Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.