LbrM.34.0820

NADH-dependent fumarate reductase-like protein

Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_104311 OG7: OG7_0003099 170 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 170 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LbrM.11.0400 ⚠ aminopeptidase, putative, metallo-peptidase,	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_001670 ↔ TCSYLVIO_008502 OG6 LdBPK_110630.1 ↔ LdBPK_350850.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_005159 +2 more	Both
LbrM.11.0410 ⚠ metallo-peptidase, Clan MF, Family M17	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_001670 ↔ TCSYLVIO_008502 OG6 LdBPK_110630.1 ↔ LdBPK_350850.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_005159 +2 more	Both
LbrM.30.0880 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_300810.1 ↔ LdBPK_350850.1 OG6 TCSYLVIO_003145 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_003145 ↔ TCSYLVIO_008502 OG7 LdBPK_300810.1 ↔ LdBPK_350850.1 +2 more	Both
LbrM.28.2630 ⚠ Vacuolar proton pump subunit B, putative	—	OG6 TCSYLVIO_002668 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_002668 ↔ TCSYLVIO_008502 OG6 Tb927.10.3650 ↔ Tb927.11.11690 OG7 Tb927.10.3650 ↔ Tb927.11.11690 +2 more	Both
LbrM.33.2840 ⚠ metallo-peptidase, Clan MF, Family M17	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_005159 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_008502 OG7 LdBPK_110630.1 ↔ LdBPK_350850.1	OG7
LbrM.28.2980 ⚠ heat-shock protein hsp70, putative (fragment)	—	OG6 TCSYLVIO_002696 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_002696 ↔ TCSYLVIO_008502	OG6
LbrM.12.0630 ⚠ alanine aminotransferase	—	OG6 Tb927.1.3950 ↔ Tb927.5.930 OG7 Tb927.1.3950 ↔ Tb927.5.930	Both
LbrM.28.2970 ⚠ heat-shock protein hsp70, putative	—	OG6 TCSYLVIO_002696 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_002696 ↔ TCSYLVIO_008502	OG6
LbrM.28.1300 ⚠ luminal binding protein 1 (BiP), putative	—	OG6 TCSYLVIO_002696 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_002696 ↔ TCSYLVIO_008502	OG6
LbrM.28.2990 ⚠ heat-shock protein hsp70, putative	—	OG6 TCSYLVIO_002696 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_002696 ↔ TCSYLVIO_008502	OG6
LbrM.22.0530 ⚠ Uncharacterised protein family UPF0066, putat	—	OG6 TCSYLVIO_001255 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_001255 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_001255 ↔ TCSYLVIO_005116 OG7 TCSYLVIO_001255 ↔ TCSYLVIO_008502	Both
LbrM.18.0730 ⚠ PA26 p53-induced protein (sestrin), putative	—	OG6 LdBPK_180660.1 ↔ LdBPK_350850.1 OG7 LdBPK_180660.1 ↔ LdBPK_350850.1	Both
LbrM.29.0290 ⚠ hypothetical protein, conserved	—	OG6 Tb927.3.5310 ↔ Tb927.5.940 OG7 Tb927.3.5310 ↔ Tb927.5.940	Both
LbrM.15.0310 ⚠ ribonucleoprotein p18, mitochondrial precurso	—	OG6 TCSYLVIO_002426 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_002426 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_002426 ↔ TCSYLVIO_005159 OG7 TCSYLVIO_002426 ↔ TCSYLVIO_008502	Both
LbrM.15.0320 ⚠ ribonucleoprotein p18, mitochondrial precurso	—	OG6 TCSYLVIO_002426 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_002426 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_002426 ↔ TCSYLVIO_005159 OG7 TCSYLVIO_002426 ↔ TCSYLVIO_008502	Both
LbrM.01.0030 ⚠ DNA-damage inducible protein DDI1-like protei	—	OG6 TCSYLVIO_003428 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_003428 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_003428 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_003428 ↔ TCSYLVIO_005116 +2 more	Both
LbrM.34.0010 ⚠ pyruvate kinase	—	OG6 Tb927.10.14140 ↔ Tb927.5.930 OG7 Tb927.10.14140 ↔ Tb927.5.930	Both
LbrM.34.0070 ⚠ pyruvate kinase, putative (fragment)	—	OG6 Tb927.10.14140 ↔ Tb927.5.930 OG7 Tb927.10.14140 ↔ Tb927.5.930	Both
LbrM.34.0060 ⚠ pyruvate kinase	—	OG6 Tb927.10.14140 ↔ Tb927.5.930 OG7 Tb927.10.14140 ↔ Tb927.5.930	Both
LbrM.34.0040 ⚠ pyruvate kinase	—	OG6 Tb927.10.14140 ↔ Tb927.5.930 OG7 Tb927.10.14140 ↔ Tb927.5.930	Both
LbrM.24.1970 ⚠ WD domain, G-beta repeat/PFU (PLAA family ubi	—	OG6 TCSYLVIO_001314 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_001314 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_001314 ↔ TCSYLVIO_005159 OG7 TCSYLVIO_001314 ↔ TCSYLVIO_008502	Both
LbrM.06.0350 ⚠ glutamine synthetase, putative	—	OG6 Tb927.5.930 ↔ Tb927.7.4970 OG6 Tb927.10.3650 ↔ Tb927.7.4970 OG7 Tb927.5.930 ↔ Tb927.7.4970 OG7 Tb927.10.3650 ↔ Tb927.7.4970	Both
LbrM.13.1540 ⚠ pyrroline-5-carboxylate reductase	—	OG6 Tb927.5.930 ↔ Tb927.7.2440 OG7 Tb927.5.930 ↔ Tb927.7.2440	Both
LbrM.22.0770 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_220710.1 ↔ LdBPK_350850.1 OG7 LdBPK_220710.1 ↔ LdBPK_350850.1	Both
LbrM.30.1350 ⚠ Zinc finger, C3HC4 type (RING finger), putati	—	OG6 TCSYLVIO_003179 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_003179 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_003179 ↔ TCSYLVIO_005116 OG7 TCSYLVIO_003179 ↔ TCSYLVIO_008502	Both
LbrM.35.2130 ⚠ 60S ribosomal protein L37a	—	OG6 LdBPK_212190.1 ↔ LdBPK_350850.1 OG7 LdBPK_212190.1 ↔ LdBPK_350850.1	Both
LbrM.33.0880 ⚠ 60S ribosomal protein L37a	—	OG6 LdBPK_212190.1 ↔ LdBPK_350850.1 OG7 LdBPK_212190.1 ↔ LdBPK_350850.1	Both
LbrM.23.0650 ⚠ poly(A)-specific ribonuclease PARN, putative	—	OG6 TCSYLVIO_000055 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_000055 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_005159 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_008502	Both
LbrM.35.6680 ⚠ poly(A)-specific ribonuclease PARN, putative	—	OG6 TCSYLVIO_000055 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_000055 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_005159 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_008502	Both
LbrM.19.0530 ⚠ polyprenyl synthase, putative	—	OG6 LdBPK_190210.1 ↔ LdBPK_350850.1 OG7 LdBPK_190210.1 ↔ LdBPK_350850.1	Both
LbrM.29.0610 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_290620.1 ↔ LdBPK_350850.1 OG7 LdBPK_290620.1 ↔ LdBPK_350850.1	Both
LbrM.22.0580 ⚠ guide RNA associated protein, GAP2, putative	—	OG6 TCSYLVIO_001262 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_001262 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_001262 ↔ TCSYLVIO_005116 OG7 TCSYLVIO_001262 ↔ TCSYLVIO_008502	Both
LbrM.21.1130 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_003107 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_005116 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_005159 +2 more	Both
LbrM.30.0540 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_003107 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_005116 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_005159 +2 more	Both
LbrM.10.1320 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_003586 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_003586 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_003586 ↔ TCSYLVIO_005159 OG7 TCSYLVIO_003586 ↔ TCSYLVIO_008502	Both
LbrM.26.1830 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_003586 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_003586 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_003586 ↔ TCSYLVIO_005159 OG7 TCSYLVIO_003586 ↔ TCSYLVIO_008502	Both
LbrM.03.0820 ⚠ inorganic pyrophosphatase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_005159 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_008502	Both
LbrM.19.0110 ⚠ acidocalcisomal pyrophosphatase	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_005159 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_008502	Both
LbrM.34.0690 ⚠ vacuolar ATP synthase subunit d, putative	—	OG6 TCSYLVIO_005104 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_005104 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_005104 ↔ TCSYLVIO_005159 OG7 TCSYLVIO_005104 ↔ TCSYLVIO_008502	Both
LbrM.35.4480 ⚠ paraflagellar rod component, putative	—	OG6 TCSYLVIO_004736 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_004736 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_004736 ↔ TCSYLVIO_008502	OG6
LbrM.13.0750 ⚠ N(2), N(2)-dimethylguanosine tRNA methyltrans	—	OG6 TCSYLVIO_002844 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_002844 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_002844 ↔ TCSYLVIO_005116 OG7 TCSYLVIO_002844 ↔ TCSYLVIO_008502	Both
LbrM.30.0640 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_003118 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_003118 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_005159 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_008502	Both
LbrM.24.2100 ⚠ tubulin folding cofactor D, putative	—	OG6 TCSYLVIO_001302 ↔ TCSYLVIO_005116 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_005116 +2 more	Both
LbrM.12.0300 ⚠ ornithine decarboxylase, putative	—	OG6 LdBPK_120105.1 ↔ LdBPK_350850.1 OG7 LdBPK_120105.1 ↔ LdBPK_350850.1	Both
LbrM.29.0550 ⚠ zinc-finger of a C2HC-type, putative	—	OG7 TCSYLVIO_006138 ↔ TCSYLVIO_008502 OG7 TCSYLVIO_005116 ↔ TCSYLVIO_006138	OG7
LbrM.21.1330 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_005118 ↔ TCSYLVIO_005299	OG7
LbrM.15.1120 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_005118 ↔ TCSYLVIO_007058	OG7
LbrM.33.2090 ⚠ dual-specificity protein kinase, putative	—	OG7 TCSYLVIO_008502 ↔ TCSYLVIO_009362 OG7 TCSYLVIO_005116 ↔ TCSYLVIO_009362	OG7
LbrM.14.1060 ⚠ protein kinase, putative	—	OG7 TCSYLVIO_008502 ↔ TCSYLVIO_009362 OG7 TCSYLVIO_005116 ↔ TCSYLVIO_009362	OG7
LbrM.15.0170 ⚠ serine/threonine-protein kinase, putative, pr	—	OG7 TCSYLVIO_008502 ↔ TCSYLVIO_009362 OG7 TCSYLVIO_005116 ↔ TCSYLVIO_009362	OG7

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