LbrM.12.0630

alanine aminotransferase
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_100524 OG7: OG7_0003566 36 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 36 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.10.0310
isocitrate dehydrogenase [NADP], mitochondria
— Both
LbrM.24.0780 ⚠
malic enzyme
— Both
LbrM.26.2160
kynureninase, putative
— Both
LbrM.14.1320 ⚠
enolase
— Both
LbrM.34.1090 ⚠
NADH-dependent fumarate reductase, putative
— Both
LbrM.34.0810 ⚠
aspartate aminotransferase, putative
— Both
LbrM.34.1100 ⚠
NADH-dependent fumarate reductase, putative
— Both
LbrM.24.0320 ⚠
fumarate hydratase, putative
— Both
LbrM.34.3250
6-phosphogluconate dehydrogenase, decarboxyla
— Both
LbrM.32.3210 ⚠
nucleoside diphosphate kinase b
— Both
LbrM.32.3200 ⚠
nucleoside diphosphate kinase b
— Both
LbrM.18.0760 ⚠
citrate synthase, putative
— Both
LbrM.34.2990
glycerol kinase, glycosomal, putative
— Both
LbrM.20.4800
cytidine triphosphate synthase, putative, CTP
— Both
LbrM.35.5430 ⚠
aldehyde dehydrogenase, putative
— OG7
LbrM.29.2220 ⚠
Aminopeptidase M1, putative
— OG7
LbrM.12.0930 ⚠
puromycin-sensitive aminopeptidase-like prote
— OG7
LbrM.34.4710 ⚠
glyceraldehyde-3-phosphate dehydrogenase-like
— OG7
LbrM.18.0570
aconitase, putative
— Both
LbrM.24.0790 ⚠
malic enzyme, putative
— Both
LbrM.14.0130 ⚠
inosine-guanine nucleoside hydrolase, putativ
— Both
LbrM.29.1930 ⚠
Fumarate hydratase class I, cytosolic
— Both
LbrM.05.0800
methylthioadenosine phosphorylase, putative
— Both
LbrM.13.0970
adenylosuccinate synthetase, putative
— Both
LbrM.14.1330 ⚠
enolase
— Both
LbrM.30.2950 ⚠
glyceraldehyde 3-phosphate dehydrogenase, gly
— Both
LbrM.18.1610 ⚠
nonspecific nucleoside hydrolase
— Both
LbrM.26.0330 ⚠
metallo-peptidase, Clan MA(E), Family M1
— Both
LbrM.24.2190
3-hydroxy-3-methylglutaryl-CoA synthase, puta
— Both
LbrM.30.2880 ⚠
aldehyde dehydrogenase, putative
— Both
LbrM.24.0370 ⚠
aspartate aminotransferase, putative
— Both
LbrM.18.0770 ⚠
citrate synthase, putative
— Both
LbrM.34.0820 ⚠
NADH-dependent fumarate reductase-like protei
— Both
LbrM.34.1110 ⚠
NADH-dependent fumarate reductase, putative
— Both
LbrM.30.3550
S-adenosylmethionine synthetase
— Both
LbrM.33.1600
glutamine aminotransferase, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.