LbrM.13.0750

N(2), N(2)-dimethylguanosine tRNA methyltransferase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101071 OG7: OG7_0004550 64 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 64 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.35.4500 ⚠
serine/threonine kinase, putative
— OG7
LbrM.13.1350 ⚠
tRNA pseudouridine synthase, putative
— Both
LbrM.18.1310
bifunctional aminoacyl-tRNA synthetase, putat
— Both
LbrM.20.5390 ⚠
calpain-like cysteine peptidase, putative, cy
— OG6
LbrM.20.5340 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LbrM.30.1350
Zinc finger, C3HC4 type (RING finger), putati
— Both
LbrM.25.1790
hypothetical protein, conserved
— Both
LbrM.34.2850 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— Both
LbrM.34.1090 ⚠
NADH-dependent fumarate reductase, putative
— Both
LbrM.34.1100 ⚠
NADH-dependent fumarate reductase, putative
— Both
LbrM.34.0890
hypothetical protein, conserved
— Both
LbrM.01.0030
DNA-damage inducible protein DDI1-like protei
— Both
LbrM.33.2190
ribosome assembly protein RRB1, putative
— Both
LbrM.24.2100
tubulin folding cofactor D, putative
— Both
LbrM.20.1840 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LbrM.10.0160
hypothetical protein, conserved
— OG7
LbrM.30.0390
kinesin, putative
— OG6
LbrM.34.1770 ⚠
protein kinase-like protein
— OG7
LbrM.14.1060 ⚠
protein kinase, putative
— OG7
LbrM.26.0440 ⚠
pseudouridylate synthase-like protein
— OG7
LbrM.33.2090 ⚠
dual-specificity protein kinase, putative
— OG7
LbrM.26.0340 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
LbrM.30.1610 ⚠
pseudouridine synthase A-like protein, putati
— OG7
LbrM.15.0170 ⚠
serine/threonine-protein kinase, putative, pr
— OG7
LbrM.29.0550 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LbrM.35.0580 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LbrM.05.0820 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LbrM.31.1600
hypothetical protein, conserved
— OG7
LbrM.35.0220 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
LbrM.14.0800 ⚠
protein kinase, putative
— OG7
LbrM.19.1300 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LbrM.35.0150 ⚠
leucine carboxyl methyltransferase, putative
— OG7
LbrM.20.5380 ⚠
calpain-like cysteine peptidase, putative, cy
— OG6
LbrM.28.0700 ⚠
Ankyrin repeats (3 copies), putative
— OG6
LbrM.28.2630
Vacuolar proton pump subunit B, putative
— Both
LbrM.26.1260 ⚠
heat shock protein 70-related protein
— OG6
LbrM.28.3030 ⚠
heat shock protein 70, putative
— Both
LbrM.28.2980 ⚠
heat-shock protein hsp70, putative (fragment)
— OG6
LbrM.28.2970 ⚠
heat-shock protein hsp70, putative
— OG6
LbrM.28.1300 ⚠
luminal binding protein 1 (BiP), putative
— OG6
LbrM.28.2990 ⚠
heat-shock protein hsp70, putative
— OG6
LbrM.22.0530
Uncharacterised protein family UPF0066, putat
— Both
LbrM.22.0580
guide RNA associated protein, GAP2, putative
— Both
LbrM.18.0090 ⚠
zinc-finger of a C2HC-type/Double zinc ribbon
— Both
LbrM.20.3260
vacuolar ATP synthase catalytic subunit A, pu
— Both
LbrM.21.1940 ⚠
protein kinase, putative
— Both
LbrM.03.0700 ⚠
6-phosphofructo-2-kinase 1
— Both
LbrM.29.0030
transcription factor-like protein
— Both
LbrM.30.3300 ⚠
Ankyrin repeats (3 copies), putative
— OG6
LbrM.21.1810
2-oxoisovalerate dehydrogenase alpha subunit,
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.