LbrM.35.0220

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_129420 OG7: OG7_0002306 145 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 145 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.34.2850 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— OG7
LbrM.33.0560 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.0150 ⚠
leucine carboxyl methyltransferase, putative
— OG7
LbrM.23.0650 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LbrM.34.1090 ⚠
NADH-dependent fumarate reductase, putative
— OG7
LbrM.01.0690 ⚠
ubiquitin activating enzyme, putative
— OG7
LbrM.30.0640 ⚠
hypothetical protein, conserved
— OG7
LbrM.29.0550 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LbrM.34.1100 ⚠
NADH-dependent fumarate reductase, putative
— OG7
LbrM.01.0030 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
LbrM.26.1830 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.0890 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.0580 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LbrM.25.0010 ⚠
beta galactofuranosyl transferase
— OG7
LbrM.05.0820 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LbrM.33.2190 ⚠
ribosome assembly protein RRB1, putative
— OG7
LbrM.34.1330 ⚠
threonyl-tRNA synthetase, putative
— OG7
LbrM.35.5420 ⚠
vacuolar protein sorting-associated protein-l
— OG7
LbrM.21.1580 ⚠
ATP synthase, putative
— OG7
LbrM.30.0540 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.34.4210 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.3910 ⚠
nucleolar protein family a, putative
— OG7
LbrM.29.0260 ⚠
TPR repeat, putative
— OG7
LbrM.35.3320 ⚠
ATP synthase, putative
— OG7
LbrM.23.0120 ⚠
GDP-mannose pyrophosphorylase
— OG7
LbrM.19.1750 ⚠
eukaryotic translation initiation factor-like
— OG7
LbrM.08.0230 ⚠
ubiquitin-activating enzyme-like protein (fra
— OG7
LbrM.32.0280 ⚠
Histone chaperone Rttp106-like, putative
— OG7
LbrM.18.0610 ⚠
hypothetical protein, conserved
— OG7
LbrM.14.0800 ⚠
protein kinase, putative
— OG7
LbrM.24.0840 ⚠
inositol polyphosphate phosphatase, putative
— OG7
LbrM.34.0820 ⚠
NADH-dependent fumarate reductase-like protei
— OG7
LbrM.35.5680 ⚠
branch point binding protein, putative
— OG7
LbrM.34.1110 ⚠
NADH-dependent fumarate reductase, putative
— OG7
LbrM.30.0530 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
LbrM.04.0500 ⚠
adenylosuccinate lyase, putative
— OG7
LbrM.34.2290 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LbrM.04.0380 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.2510 ⚠
hypothetical protein, conserved
— OG7
LbrM.28.1010 ⚠
oxidoreductase-like protein
— OG7
LbrM.33.3230 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.0200 ⚠
PUB domain containing protein, putative
— OG7
LbrM.29.2680 ⚠
Triglyceride lipase, putative
— OG7
LbrM.32.2970 ⚠
hypothetical protein, conserved
— OG7
LbrM.32.0260 ⚠
hypothetical protein, conserved
— OG7
LbrM.06.0170 ⚠
hypothetical protein, conserved
— OG7
LbrM.24.2100 ⚠
tubulin folding cofactor D, putative
— OG7
LbrM.20.3260 ⚠
vacuolar ATP synthase catalytic subunit A, pu
— OG7
LbrM.30.3250 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.2310 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.