LbrM.04.0380

hypothetical protein, conserved
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_478914 OG7: OG7_0083988 86 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 86 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.28.1010
oxidoreductase-like protein
— Both
LbrM.34.0940 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
LbrM.21.0910 ⚠
Temperature dependent protein affecting M2 ds
— OG7
LbrM.32.1720 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LbrM.33.3240 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.1640 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
LbrM.35.3290 ⚠
fibrillarin
— Both
LbrM.35.0200
PUB domain containing protein, putative
— Both
LbrM.34.1630
casein kinase II, putative
— OG6
LbrM.09.0990
translation-associated element 2, putative
— Both
LbrM.17.0410
hypothetical protein, conserved
— Both
LbrM.30.0160 ⚠
Leucine-rich repeat, ribonuclease inhibitor s
— OG7
LbrM.33.3230 ⚠
hypothetical protein, conserved
— Both
LbrM.08.0110
hypothetical protein, unknown function
— Both
LbrM.08.0730
Beta-lactamase superfamily domain containing
— Both
LbrM.32.0060 ⚠
nuclear segregation protein, putative
— Both
LbrM.15.0590
hypothetical protein, conserved
— Both
LbrM.33.2150
hypothetical protein, conserved
— Both
LbrM.34.2850 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— Both
LbrM.30.2510
hypothetical protein, conserved
— Both
LbrM.26.2040
hypothetical protein, conserved
— Both
LbrM.29.2640
serine/threonine-protein kinase Nek, putative
— OG6
LbrM.19.0180 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.2860 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
LbrM.35.0220 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
LbrM.26.0340 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
LbrM.35.0150 ⚠
leucine carboxyl methyltransferase, putative
— OG7
LbrM.26.0520 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.1320 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
LbrM.34.4940 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LbrM.17.0210 ⚠
WD domain, G-beta repeat, putative
— OG7
LbrM.09.1220 ⚠
hypothetical protein, conserved
— OG7
LbrM.25.1360 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.2690
Stabilization of polarity axis, putative
— Both
LbrM.24.0630 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LbrM.10.0120 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LbrM.32.0850 ⚠
cyclin 9, putative
— OG7
LbrM.28.1500 ⚠
hypothetical protein, conserved
— OG7
LbrM.21.0460 ⚠
Peptidase C19, ubiquitin carboxyl-terminal hy
— OG7
LbrM.05.0150 ⚠
hypothetical protein, conserved
— OG7
LbrM.29.1190 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LbrM.35.4810 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LbrM.20.3690 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
LbrM.35.5920 ⚠
Cyclin 12, L-type
— Both
LbrM.35.6450
hypothetical protein, conserved
— Both
LbrM.13.1210
hypothetical protein, conserved
— Both
LbrM.15.1050
glutamate dehydrogenase
— Both
LbrM.30.3470 ⚠
protein mkt1, putative
— Both
LbrM.28.0240
hypothetical protein, unknown function
— Both
LbrM.09.1030
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.