LbrM.33.2190

ribosome assembly protein RRB1, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_102504 OG7: OG7_0007856 241 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 241 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.18.0610
hypothetical protein, conserved
— Both
LbrM.08.0230 ⚠
ubiquitin-activating enzyme-like protein (fra
— Both
LbrM.22.0580
guide RNA associated protein, GAP2, putative
— Both
LbrM.01.0690 ⚠
ubiquitin activating enzyme, putative
— OG7
LbrM.18.1310
bifunctional aminoacyl-tRNA synthetase, putat
— Both
LbrM.08.0470
WD domain, G-beta repeat, putative
— Both
LbrM.26.0440 ⚠
pseudouridylate synthase-like protein
— OG7
LbrM.19.1300 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LbrM.13.1350 ⚠
tRNA pseudouridine synthase, putative
— Both
LbrM.30.0640
hypothetical protein, conserved
— Both
LbrM.18.1380
hypothetical protein, conserved
— Both
LbrM.30.1610 ⚠
pseudouridine synthase A-like protein, putati
— Both
LbrM.33.2670 ⚠
heat shock protein, putative
— OG7
LbrM.11.0690
hypothetical protein, conserved
— Both
LbrM.28.2940
hypothetical protein, conserved
— OG7
LbrM.35.4500 ⚠
serine/threonine kinase, putative
— OG7
LbrM.10.0160
hypothetical protein, conserved
— OG7
LbrM.35.1280 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
LbrM.35.3150 ⚠
hypothetical protein, conserved, predicted zi
— OG7
LbrM.09.0340 ⚠
Ring finger domain containing protein, putati
— OG7
LbrM.27.1300 ⚠
RING-H2 zinc finger, putative
— OG7
LbrM.21.1510 ⚠
Ring finger domain containing protein, putati
— OG7
LbrM.17.0040 ⚠
Ring finger domain containing protein, putati
— OG7
LbrM.35.0090 ⚠
PUF1, putative
— OG7
LbrM.06.0050 ⚠
pumilio/PUF RNA binding protein 5, putative
— OG7
LbrM.21.1990 ⚠
pumillio protein 3, putative
— OG7
LbrM.12.0400 ⚠
pumillio protein 4, putative
— OG7
LbrM.20.5610 ⚠
RNA-binding regulatory protein, putative, pum
— OG7
LbrM.20.5580 ⚠
pumilio protein, putative, RNA-binding regula
— OG7
LbrM.30.0820 ⚠
co-chaperone GrpE, putative
— OG7
LbrM.35.7070 ⚠
replication factor C subunit 3, putative
— OG7
LbrM.27.0660 ⚠
replication factor C, subunit 4, putative
— OG7
LbrM.20.5250 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.2590 ⚠
replication factor C, subunit 2, putative
— OG7
LbrM.17.0530 ⚠
ATPase family associated with various cellula
— OG7
LbrM.34.3160 ⚠
replication factor C, subunit 3, putative
— OG7
LbrM.23.0650 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LbrM.30.0540 ⚠
aspartyl-tRNA synthetase, putative
— Both
LbrM.21.1130 ⚠
aspartyl-tRNA synthetase, putative
— Both
LbrM.31.1330 ⚠
amidohydrolase, putative
— Both
LbrM.20.5910 ⚠
amidohydrolase, putative
— Both
LbrM.20.5920 ⚠
amidohydrolase, putative
— Both
LbrM.35.6680 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LbrM.30.1491 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— Both
LbrM.22.1170 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LbrM.11.0790 ⚠
adaptin-related protein-like protein
— OG7
LbrM.19.1330
hypothetical protein, unknown function
— Both
LbrM.30.1350
Zinc finger, C3HC4 type (RING finger), putati
— Both
LbrM.30.0830 ⚠
heat shock protein grpe, co-chaperone, GrpE,
— Both
LbrM.20.5930 ⚠
amidohydrolase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.