LbrM.30.0830

heat shock protein grpe, co-chaperone, GrpE, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_188614 OG7: OG7_0004892 135 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 135 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.30.1491 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— OG7
LbrM.34.4440 ⚠
sm-f snRNP core complex protein, putative
— OG7
LbrM.25.2290 ⚠
LSM domain containing protein, putative
— OG7
LbrM.30.1330 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LbrM.20.1840 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LbrM.28.2370 ⚠
Mitochondrial import receptor subunit ATOM69,
— OG7
LbrM.21.1130 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.30.0540 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.27.1770 ⚠
BRO1-like domain/ALIX V-shaped domain binding
— OG7
LbrM.05.0680 ⚠
hypothetical protein, conserved
— OG7
LbrM.22.0140 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.2970 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LbrM.23.0700 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LbrM.28.0960 ⚠
ribonucleoside-diphosphate reductase large ch
— OG7
LbrM.20.5270 ⚠
hypothetical protein, conserved
— OG7
LbrM.06.0920 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.2170 ⚠
TLD, putative
— OG7
LbrM.33.2840 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LbrM.34.1640 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
LbrM.29.2270 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LbrM.25.1030 ⚠
GIY-YIG catalytic domain containing protein,
— OG7
LbrM.20.5930 ⚠
amidohydrolase, putative
— OG7
LbrM.27.1450 ⚠
arginyl-tRNA synthetase, putative
— OG7
LbrM.21.0600 ⚠
Lupus La protein homolog, putative
— OG7
LbrM.04.0070 ⚠
cAMP-specific phosphodiesterase, putative
— OG7
LbrM.20.3690 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
LbrM.15.1240 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
LbrM.33.2670 ⚠
heat shock protein, putative
— OG7
LbrM.35.5390 ⚠
VHS domain containing protein, putative
— OG7
LbrM.33.0350 ⚠
heat shock protein 83-1
— OG7
LbrM.32.1380 ⚠
ADP-ribosylation factor GTPase activating pro
— OG7
LbrM.11.0400 ⚠
aminopeptidase, putative, metallo-peptidase,
— OG7
LbrM.18.1210 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
LbrM.17.1090 ⚠
Mak10 subunit, NatC N(alpha)-terminal acetylt
— OG7
LbrM.14.1490 ⚠
serine hydroxymethyltranferase (SHMT-S)
— OG7
LbrM.11.0410 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LbrM.17.1400 ⚠
hypothetical protein, conserved
— OG7
LbrM.29.2510 ⚠
NOL1/NOP2/sun family, putative
— OG7
LbrM.35.4280 ⚠
hypothetical protein, conserved
— OG7
LbrM.15.0300 ⚠
replication Factor A 28 kDa subunit, putative
— OG7
LbrM.15.0750 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.5920 ⚠
amidohydrolase, putative
— OG7
LbrM.20.5910 ⚠
amidohydrolase, putative
— OG7
LbrM.21.0900 ⚠
methionyl-tRNA synthetase, putative
— OG7
LbrM.15.0040 ⚠
Possible lysine decarboxylase, putative
— OG7
LbrM.30.0780 ⚠
nuclear movement protein, putative, NUDC-like
— OG7
LbrM.35.5900 ⚠
isoleucyl-tRNA synthetase, putative
— OG7
LbrM.29.0270 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LbrM.32.1740 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LbrM.34.0410 ⚠
thioredoxin, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.