LbrM.27.1770

BRO1-like domain/ALIX V-shaped domain binding to HIV, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_102685 OG7: OG7_0003119 20 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 20 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.29.1020 ⚠
5-histidylcysteine sulfoxide synthase, putati
— Both
LbrM.09.0850 ⚠
oligopeptidase b
— OG7
LbrM.06.0320 ⚠
oligopeptidase B-like protein, serine peptida
— OG7
LbrM.12.0930 ⚠
puromycin-sensitive aminopeptidase-like prote
— OG7
LbrM.29.2220 ⚠
Aminopeptidase M1, putative
— OG7
LbrM.30.0830 ⚠
heat shock protein grpe, co-chaperone, GrpE,
— OG7
LbrM.05.0770 ⚠
Mitochondrial glycoprotein, putative
— OG7
LbrM.22.1360 ⚠
Mitochondrial glycoprotein, putative
— OG7
LbrM.26.1920 ⚠
methyltransferase domain containing protein,
— OG7
LbrM.26.0330 ⚠
metallo-peptidase, Clan MA(E), Family M1
— Both
LbrM.30.2420 ⚠
heat shock 70-related protein 1, mitochondria
— Both
LbrM.23.0600
5'-3' exoribonuclease C, putative
— Both
LbrM.35.7100 ⚠
prolyl endopeptidase
— Both
LbrM.30.2430 ⚠
heat shock 70-related protein 1, mitochondria
— Both
LbrM.30.1090 ⚠
p22 protein precursor, putative
— Both
LbrM.30.2410 ⚠
heat shock 70-related protein 1, mitochondria
— Both
LbrM.30.2440 ⚠
heat shock 70-related protein 1, mitochondria
— Both
LbrM.30.2500 ⚠
heat shock 70-related protein 1, mitochondria
— Both
LbrM.30.2450 ⚠
heat shock 70-related protein 1, mitochondria
— Both
LbrM.30.0820 ⚠
co-chaperone GrpE, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.