LbrM.04.0070

cAMP-specific phosphodiesterase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_146459 OG7: OG7_0042785 92 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:
Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 92 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.34.1640 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
LbrM.15.1240 ⚠
cysteine peptidase, Clan CA, family C19, puta
— Both
LbrM.20.3690 ⚠
cysteine peptidase, Clan CA, family C19, puta
— Both
LbrM.34.2970 ⚠
ubiquitin-activating enzyme E1, putative
— Both
LbrM.29.1920
protein farnesyltransferase alpha subunit, pu
— Both
LbrM.15.0750
hypothetical protein, conserved
— Both
LbrM.30.0820 ⚠
co-chaperone GrpE, putative
— Both
LbrM.28.2370
Mitochondrial import receptor subunit ATOM69,
— Both
LbrM.01.0480 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
LbrM.20.0990
Carnosine N-methyltransferase, putative
— Both
LbrM.03.0340
protein kinase, putative
— Both
LbrM.11.0490
anion-transporting ATPase-like protein
— Both
LbrM.05.0680
hypothetical protein, conserved
— Both
LbrM.32.1720 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LbrM.23.0700 ⚠
ubiquitin-activating enzyme E1, putative
— Both
LbrM.30.2700
small glutamine-rich tetratricopeptide repeat
— OG6
LbrM.30.3460
T-complex protein 11, putative
— Both
LbrM.17.1400
hypothetical protein, conserved
— Both
LbrM.15.0300
replication Factor A 28 kDa subunit, putative
— Both
LbrM.29.2270
ubiquitin carboxyl-terminal hydrolase, putati
— Both
LbrM.35.3290 ⚠
fibrillarin
— Both
LbrM.34.1630
casein kinase II, putative
— OG6
LbrM.09.0990
translation-associated element 2, putative
— Both
LbrM.17.0410
hypothetical protein, conserved
— Both
LbrM.19.0180 ⚠
hypothetical protein, conserved
— OG7
LbrM.29.0270 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LbrM.32.1740 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LbrM.28.1940 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LbrM.13.0530 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LbrM.30.0830 ⚠
heat shock protein grpe, co-chaperone, GrpE,
— OG7
LbrM.20.2860 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
LbrM.30.1320 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
LbrM.34.4940 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LbrM.17.0210 ⚠
WD domain, G-beta repeat, putative
— OG7
LbrM.09.1220 ⚠
hypothetical protein, conserved
— OG7
LbrM.25.1360 ⚠
hypothetical protein, conserved
— OG7
LbrM.33.3240 ⚠
hypothetical protein, conserved
— OG7
LbrM.24.0630 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LbrM.10.0120 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LbrM.32.0850 ⚠
cyclin 9, putative
— OG7
LbrM.28.1500 ⚠
hypothetical protein, conserved
— OG7
LbrM.21.0460 ⚠
Peptidase C19, ubiquitin carboxyl-terminal hy
— OG7
LbrM.29.1190 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LbrM.35.4810 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LbrM.34.0940 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
LbrM.21.0910 ⚠
Temperature dependent protein affecting M2 ds
— OG7
LbrM.33.3230 ⚠
hypothetical protein, conserved
— Both
LbrM.32.1250
Aminoacyl-tRNA editing domain containing prot
— Both
LbrM.30.2390
hypothetical protein, conserved
— Both
LbrM.08.1000
hypothetical protein, unknown function
— Both
Page 1 of 2
Next →
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.