LbrM.35.6680

poly(A)-specific ribonuclease PARN, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_102215 OG7: OG7_0005534 206 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 206 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.20.1840 ⚠
asparaginyl-tRNA synthetase, putative
— Both
LbrM.18.1100 ⚠
5-oxoprolinase, putative
— Both
LbrM.24.2100 ⚠
tubulin folding cofactor D, putative
— Both
LbrM.24.0010 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— +1 more Both
LbrM.20.3510 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LbrM.12.0270 ⚠
cysteinyl-tRNA synthetase, putative
— Both
LbrM.19.1320 ⚠
phenylalanyl-tRNA synthetase, putative
— Both
LbrM.21.1130 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.20.4500 ⚠
developmentally regulated phosphoprotein-like
— Both
LbrM.30.0540 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.30.1210 ⚠
WW domain containing protein, putative
— OG7
LbrM.25.1890 ⚠
Leucine Rich repeats (2 copies), putative
— Both
LbrM.07.0290 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LbrM.34.5330 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.35.1390 ⚠
fructose-1,6-bisphosphate aldolase
— OG7
LbrM.27.2700 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LbrM.31.0170 ⚠
diphthamide synthesis protein
— OG7
LbrM.11.0070 ⚠
Domain of unknown function(DUF2779), putative
— OG7
LbrM.20.4970 ⚠
tubulin-tyrosine ligase, putative
— OG7
LbrM.16.0390 ⚠
tubulin tyrosine ligase, putative
— OG7
LbrM.11.0620 ⚠
tubulin-tyrsoine ligase-like protein (fragmen
— OG7
LbrM.29.0520 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LbrM.34.4880 ⚠
tubulin tyrosine ligase, putative
— OG7
LbrM.28.0170 ⚠
RNA binding protein, putative
— OG7
LbrM.20.3660 ⚠
geranylgeranyltransferase, putative
— OG7
LbrM.11.0080 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LbrM.30.2230 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LbrM.32.3180 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LbrM.18.0390 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LbrM.18.1140 ⚠
cholinephosphate cytidylyltransferase A, puta
— OG7
LbrM.04.0360 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LbrM.30.1330 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LbrM.30.0640 ⚠
hypothetical protein, conserved
— Both
LbrM.34.4240 ⚠
hypothetical protein, conserved
— OG7
LbrM.18.0370 ⚠
ATP12 chaperone protein, putative
— Both
LbrM.35.2490 ⚠
developmentally regulated GTP-binding protein
— Both
LbrM.30.0880 ⚠
hypothetical protein, conserved
— Both
LbrM.33.0340 ⚠
heat shock protein 83, heat shock protein 83-
— +2 more Both
LbrM.05.0180 ⚠
dihydrolipoamide branched chain transacylase,
— Both
LbrM.33.0330 ⚠
heat shock protein 83-1
— +2 more Both
LbrM.35.2630 ⚠
serine peptidase, Clan SC, Family S9B
— Both
LbrM.35.7120 ⚠
beta adaptin, putative
— Both
LbrM.34.1090 ⚠
NADH-dependent fumarate reductase, putative
— Both
LbrM.11.0410 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
LbrM.34.1390 ⚠
choline/ethanolamine kinase, putative
— Both
LbrM.01.0190 ⚠
LSM domain containing protein, putative
— OG7
LbrM.29.1160 ⚠
Ankyrin repeats (3 copies), putative
— Both
LbrM.32.0800 ⚠
U6 snRNA-associated Sm-like protein LSm4p
— Both
LbrM.28.0460 ⚠
DIS3-like exonuclease, putative
— OG7
LbrM.34.1330 ⚠
threonyl-tRNA synthetase, putative
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.