LbrM.28.0460

DIS3-like exonuclease, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_102526 OG7: OG7_0002439 235 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 235 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.11.0400 ⚠
aminopeptidase, putative, metallo-peptidase,
— OG7
LbrM.31.1330 ⚠
amidohydrolase, putative
— Both
LbrM.14.1540 ⚠
myo-inositol-1-phosphate synthase, inositol-3
— +1 more Both
LbrM.33.1670 ⚠
protein kinase
— OG7
LbrM.20.5910 ⚠
amidohydrolase, putative
— Both
LbrM.20.5920 ⚠
amidohydrolase, putative
— Both
LbrM.33.2840 ⚠
metallo-peptidase, Clan MF, Family M17
— +1 more Both
LbrM.20.5930 ⚠
amidohydrolase, putative
— Both
LbrM.34.4530 ⚠
hypothetical protein, conserved
— +1 more Both
LbrM.25.0750 ⚠
protein kinase, putative
— +1 more Both
LbrM.15.0700 ⚠
hypothetical protein, conserved
— Both
LbrM.30.1491 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— Both
LbrM.11.0410 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LbrM.35.0560 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LbrM.29.2130 ⚠
cdc2-related kinase 10, putative
— OG7
LbrM.19.1790 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
LbrM.13.0460 ⚠
hypothetical protein, conserved
— OG7
LbrM.29.2030 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.4240 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.0780 ⚠
nuclear movement protein, putative, NUDC-like
— OG7
LbrM.26.1280 ⚠
hypothetical protein, unknown function
— OG7
LbrM.18.1140 ⚠
cholinephosphate cytidylyltransferase A, puta
— OG7
LbrM.30.0830 ⚠
heat shock protein grpe, co-chaperone, GrpE,
— OG7
LbrM.23.0330 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LbrM.33.0320 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LbrM.21.0070 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.2810 ⚠
GTPase activator-like protein
— OG7
LbrM.16.1170 ⚠
WW domain containing protein, putative
— OG7
LbrM.14.1340 ⚠
ras-like small GTPases, putative
— OG7
LbrM.20.3010 ⚠
cleavage and polyadenylation specificity fact
— OG7
LbrM.33.1980 ⚠
protein kinase, putative
— OG7
LbrM.35.6680 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LbrM.35.1020 ⚠
SNF1-related protein kinases, putative
— OG7
LbrM.23.0650 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LbrM.34.2571 ⚠
ankyrin repeat protein, putative
— OG7
LbrM.32.1960 ⚠
hypothetical protein, conserved
— OG7
LbrM.28.1460 ⚠
Ankyrin repeats (3 copies)/DHHC palmitoyltran
— OG7
LbrM.17.1240 ⚠
NOL1/NOP2/sun family, putative
— OG7
LbrM.04.1210 ⚠
tRNA nucleotidyltransferase, putative
— OG7
LbrM.03.0170 ⚠
ABC transporter protein, putative
— OG7
LbrM.13.0370 ⚠
Uncharacterized ACR, COG1678, putative
— OG7
LbrM.21.0060 ⚠
hypothetical protein, conserved
— OG7
LbrM.29.0780 ⚠
heat shock protein 90, putative
— OG7
LbrM.35.1540 ⚠
The ARF-like 2 binding protein BART, putative
— OG7
LbrM.20.3130 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LbrM.04.0570 ⚠
palmitoyl acyltransferase 1, putative
— OG7
LbrM.19.1260 ⚠
FYVE zinc finger, putative
— OG7
LbrM.18.1210 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
LbrM.33.0150 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LbrM.28.2190 ⚠
protein lipid droplet kinase (LDK)
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.