LbrM.33.1670

protein kinase
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_479008 OG7: OG7_0005083 148 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 148 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.34.4530 ⚠
hypothetical protein, conserved
— Both
LbrM.04.0360 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LbrM.28.0460 ⚠
DIS3-like exonuclease, putative
— OG7
LbrM.14.1540 ⚠
myo-inositol-1-phosphate synthase, inositol-3
— Both
LbrM.28.0340 ⚠
rrp44p homologue, putative
— Both
LbrM.24.1190 ⚠
hypothetical protein, conserved
— OG7
LbrM.03.0070 ⚠
Met-10+ like-protein, putative
— OG7
LbrM.35.6390 ⚠
rab-like GTPase activating protein, putative
— OG7
LbrM.35.6380 ⚠
disgorgin, putative
— OG7
LbrM.30.1240 ⚠
importin alpha, putative
— OG7
LbrM.35.5900 ⚠
isoleucyl-tRNA synthetase, putative
— OG7
LbrM.20.1840 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LbrM.21.1130 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.30.0710 ⚠
histidyl-tRNA synthetase, putative
— OG7
LbrM.22.0290 ⚠
hypothetical protein, conserved
— OG7
LbrM.03.0820 ⚠
inorganic pyrophosphatase, putative
— OG7
LbrM.30.0540 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.19.0110 ⚠
acidocalcisomal pyrophosphatase
— OG7
LbrM.17.0330 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LbrM.20.1170 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LbrM.25.2000 ⚠
hypothetical protein, conserved
— OG7
LbrM.22.0420 ⚠
Putative tRNA binding domain containing prote
— OG7
LbrM.16.1160 ⚠
tyrosyl or methionyl-tRNA synthetase-like pro
— OG7
LbrM.28.2560 ⚠
serine hydroxymethyltransferase (SHMT-L)
— OG7
LbrM.14.0460 ⚠
N-terminal conserved domain of Nudc./CS domai
— OG7
LbrM.30.3480 ⚠
DNA ligase I, putative
— OG7
LbrM.31.2160 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LbrM.35.2630 ⚠
serine peptidase, Clan SC, Family S9B
— OG7
LbrM.35.0560 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LbrM.35.0200 ⚠
PUB domain containing protein, putative
— OG7
LbrM.14.1560 ⚠
tyrosyl-tRNA synthetase, putative
— OG7
LbrM.23.0120 ⚠
GDP-mannose pyrophosphorylase
— OG7
LbrM.14.1490 ⚠
serine hydroxymethyltranferase (SHMT-S)
— OG7
LbrM.29.0070 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LbrM.23.0330 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LbrM.20.5870 ⚠
tRNA (Uracil-5-)-methyltransferase, putative
— OG7
LbrM.21.0900 ⚠
methionyl-tRNA synthetase, putative
— OG7
LbrM.30.0780 ⚠
nuclear movement protein, putative, NUDC-like
— OG7
LbrM.35.4340 ⚠
glycosyl hydrolase-like protein
— OG7
LbrM.31.3350 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.3120 ⚠
valyl-tRNA synthetase, putative
— OG7
LbrM.21.0060 ⚠
hypothetical protein, conserved
— OG7
LbrM.06.0930 ⚠
glucosamine-fructose-6-phosphate aminotransfe
— OG7
LbrM.05.0790 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.0390 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.2410 ⚠
NOL1/NOP2/sun family, putative
— OG7
LbrM.18.1210 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
LbrM.17.1240 ⚠
NOL1/NOP2/sun family, putative
— OG7
LbrM.21.0070 ⚠
hypothetical protein, conserved
— OG7
LbrM.29.2510 ⚠
NOL1/NOP2/sun family, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.