LbrM.14.1540

myo-inositol-1-phosphate synthase, inositol-3-phosphate synthase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_100830 OG7: OG7_0006574 180 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 180 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.19.1110 ⚠
ABC transport system ATP-binding protein, put
— Both
LbrM.11.0800
pyruvate phosphate dikinase, putative
— Both
LbrM.04.0360 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LbrM.34.4530
hypothetical protein, conserved
— Both
LbrM.03.0170 ⚠
ABC transporter protein, putative
— OG7
LbrM.33.0320 ⚠
ATP-binding cassette sub-family F member 1, p
— Both
LbrM.23.0120
GDP-mannose pyrophosphorylase
— Both
LbrM.25.0750 ⚠
protein kinase, putative
— Both
LbrM.28.0460 ⚠
DIS3-like exonuclease, putative
— +1 more Both
LbrM.33.1670 ⚠
protein kinase
— Both
LbrM.28.0340 ⚠
rrp44p homologue, putative
— Both
LbrM.30.0550
hypothetical protein, conserved
— Both
LbrM.12.0300
ornithine decarboxylase, putative
— Both
LbrM.19.0110 ⚠
acidocalcisomal pyrophosphatase
— Both
LbrM.03.0820 ⚠
inorganic pyrophosphatase, putative
— Both
LbrM.32.4220
Gar1/Naf1 RNA binding region, putative
— Both
LbrM.35.5900
isoleucyl-tRNA synthetase, putative
— Both
LbrM.05.0790
hypothetical protein, conserved
— Both
LbrM.22.1440
alanyl-tRNA synthetase, putative
— Both
LbrM.25.0170 ⚠
cleavage and polyadenylation specificity fact
— Both
LbrM.27.2600 ⚠
TPR-repeat protein, putative
— OG6
LbrM.35.0120 ⚠
stress-inducible protein STI1 homolog
— OG6
LbrM.29.2090
UDP-glucose:glycoprotein glucosyltransferase,
— Both
LbrM.29.2510 ⚠
NOL1/NOP2/sun family, putative
— Both
LbrM.35.2410 ⚠
NOL1/NOP2/sun family, putative
— Both
LbrM.34.0420
hypothetical protein, conserved
— Both
LbrM.22.1120 ⚠
translation initiation factor IF-2, putative
— Both
LbrM.18.0110 ⚠
alpha glucosidase II subunit, putative
— Both
LbrM.35.5860
adenylyl cyclase-associated protein, putative
— Both
LbrM.24.0130
ankyrin/TPR repeat protein
— OG6
LbrM.20.5920 ⚠
amidohydrolase, putative
— Both
LbrM.20.5910 ⚠
amidohydrolase, putative
— Both
LbrM.29.1320 ⚠
Hsp70 protein/TPR repeat, putative
— Both
LbrM.30.1980
cysteine peptidase, Clan CA, family C2, putat
— OG6
LbrM.20.1180
hypothetical protein, conserved
— Both
LbrM.27.2750 ⚠
ATP-dependent Clp protease subunit, heat shoc
— Both
LbrM.17.1550 ⚠
zinc-finger protein ZPR1, putative
— Both
LbrM.26.1180 ⚠
RNA pseudouridylate synthase, putative
— Both
LbrM.24.1960 ⚠
cyclin 10
— Both
LbrM.27.1820 ⚠
hypothetical protein, conserved
— Both
LbrM.34.0740
proteasome activator protein pa26, putative
— Both
LbrM.34.2220
ATP-dependent RNA helicase-like protein
— OG6
LbrM.17.0630 ⚠
Acyl CoA binding protein, putative
— OG7
LbrM.25.0920
hypothetical protein, conserved
— Both
LbrM.30.1590
phosphopantothenoylcysteine decarboxylase, pu
— Both
LbrM.16.0320 ⚠
Met-10+ like-protein, putative
— Both
LbrM.34.1120 ⚠
pre-mRNA splicing factor ATP-dependent RNA he
— OG6
LbrM.31.1330 ⚠
amidohydrolase, putative
— Both
LbrM.25.1690
eukaryotic translation initiation factor 3 su
— Both
LbrM.30.3060
tRNA (Guanine-1)-methyltransferase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.