LbrM.04.0360

mitochondrial exoribonuclease DSS-1, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_106276 OG7: OG7_0002439 229 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 229 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.25.0750 ⚠
protein kinase, putative
— OG7
LbrM.33.2840 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LbrM.20.5920 ⚠
amidohydrolase, putative
— OG7
LbrM.20.5910 ⚠
amidohydrolase, putative
— OG7
LbrM.14.1540 ⚠
myo-inositol-1-phosphate synthase, inositol-3
— OG7
LbrM.20.5930 ⚠
amidohydrolase, putative
— OG7
LbrM.11.0410 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LbrM.31.1330 ⚠
amidohydrolase, putative
— OG7
LbrM.33.1670 ⚠
protein kinase
— OG7
LbrM.30.1491 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— OG7
LbrM.34.4530 ⚠
hypothetical protein, conserved
— OG7
LbrM.15.0700 ⚠
hypothetical protein, conserved
— OG7
LbrM.11.0400 ⚠
aminopeptidase, putative, metallo-peptidase,
— OG7
LbrM.30.1030 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.26.1010 ⚠
glucosidase II beta subunit-like protein, put
— OG7
LbrM.32.4220 ⚠
Gar1/Naf1 RNA binding region, putative
— OG7
LbrM.17.0610 ⚠
Acyl CoA binding protein, putative
— OG7
LbrM.09.0830 ⚠
acyl-CoA binding protein, putative
— OG7
LbrM.20.2160 ⚠
acyl-CoA binding protein, putative
— OG7
LbrM.22.1440 ⚠
alanyl-tRNA synthetase, putative
— OG7
LbrM.17.0630 ⚠
Acyl CoA binding protein, putative
— OG7
LbrM.11.0690 ⚠
hypothetical protein, conserved
— OG7
LbrM.19.1230 ⚠
peptidyl-prolyl cis-trans isomerase, macropha
— OG7
LbrM.20.1180 ⚠
hypothetical protein, conserved
— OG7
LbrM.29.1320 ⚠
Hsp70 protein/TPR repeat, putative
— OG7
LbrM.30.0550 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.1590 ⚠
phosphopantothenoylcysteine decarboxylase, pu
— OG7
LbrM.10.0990 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LbrM.22.1310 ⚠
fk506-binding protein 1-like protein
— OG7
LbrM.30.3060 ⚠
tRNA (Guanine-1)-methyltransferase, putative
— OG7
LbrM.31.1630 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.6540 ⚠
flagellum transition zone component, putative
— OG7
LbrM.14.1240 ⚠
EAP30/Vps36 family, putative
— OG7
LbrM.35.0310 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
LbrM.29.2130 ⚠
cdc2-related kinase 10, putative
— OG7
LbrM.19.1790 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
LbrM.34.0390 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.2630 ⚠
acyl-CoA dehydrogenase, putative
— OG7
LbrM.29.0070 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LbrM.14.1490 ⚠
serine hydroxymethyltranferase (SHMT-S)
— OG7
LbrM.33.0320 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LbrM.23.0120 ⚠
GDP-mannose pyrophosphorylase
— OG7
LbrM.21.0070 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.2810 ⚠
GTPase activator-like protein
— OG7
LbrM.30.0540 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.20.4450 ⚠
deoxyhypusine synthase, putative
— OG7
LbrM.20.3010 ⚠
cleavage and polyadenylation specificity fact
— OG7
LbrM.14.1340 ⚠
ras-like small GTPases, putative
— OG7
LbrM.23.0330 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LbrM.16.1170 ⚠
WW domain containing protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.