LbrM.34.2220

ATP-dependent RNA helicase-like protein
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_146576 OG7: OG7_0000698 107 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 107 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.33.2210 ⚠
phosphoribosyl transferase, putative, phospho
— OG6
LbrM.14.0420
Protein of unknown function (DUF1253), putati
— OG6
LbrM.17.0960
Phosphorylated CTD interacting factor 1 WW do
— OG6
LbrM.29.2130
cdc2-related kinase 10, putative
— OG6
LbrM.30.0550
hypothetical protein, conserved
— OG6
LbrM.13.0460
hypothetical protein, conserved
— OG6
LbrM.14.1540
myo-inositol-1-phosphate synthase, inositol-3
— OG6
LbrM.35.5650 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG6
LbrM.32.3750 ⚠
exosome-associated protein 2, putative
— OG6
LbrM.08.0900
phosphoribosylpyrophosphate synthetase
— OG6
LbrM.31.3340
acetyl-CoA carboxylase
— OG6
LbrM.21.1320
T-complex protein 1, delta subunit, putative
— OG6
LbrM.20.2660
exosome subunit rrp6p homologue, putative
— OG6
LbrM.12.0040
proteasome beta-1 subunit, putative
— OG6
LbrM.34.3820
proteasome beta 2 subunit, putative
— OG6
LbrM.22.1490 ⚠
exosome complex exonuclease RRP45 homolog, pu
— OG6
LbrM.19.0060
hypothetical protein, conserved
— OG6
LbrM.28.0120
proteasome beta 3 subunit, putative
— OG6
LbrM.14.1140
hypothetical protein, conserved
— OG6
LbrM.03.0590
DEAD/DEAH box helicase, putative
— OG6
LbrM.21.2010
proteasome alpha 2 subunit, putative
— OG6
LbrM.32.3560
chaperonin alpha subunit, putative
— OG6
LbrM.29.1550
hypothetical protein, conserved
— OG6
LbrM.19.0080
proteasome alpha 7 subunit, putative
— OG6
LbrM.34.4810
proteasome alpha 1 subunit, putative
— OG6
LbrM.20.0320
eukaryotic translation initiation factor 5, p
— OG6
LbrM.03.0140
acetyltransferase, putative
— OG6
LbrM.27.2130
small nuclear ribonucleoprotein protein, puta
— OG6
LbrM.12.0300
ornithine decarboxylase, putative
— OG6
LbrM.25.0360
translation initiation factor SUI1, putative
— OG6
LbrM.15.0090
ATP-dependent protease ATPase subunit HslU1,
— OG6
LbrM.28.0340
rrp44p homologue, putative
— OG6
LbrM.29.0610
hypothetical protein, conserved
— OG6
LbrM.19.0530
polyprenyl synthase, putative
— OG6
LbrM.25.0680
DNL zinc finger, putative
— OG6
LbrM.25.0970
hypothetical protein, conserved
— OG6
LbrM.31.1330 ⚠
amidohydrolase, putative
— OG6
LbrM.20.5910 ⚠
amidohydrolase, putative
— OG6
LbrM.20.5920 ⚠
amidohydrolase, putative
— OG6
LbrM.30.1491 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— OG6
LbrM.20.5930 ⚠
amidohydrolase, putative
— OG6
LbrM.34.1120 ⚠
pre-mRNA splicing factor ATP-dependent RNA he
— OG6
LbrM.18.0730
PA26 p53-induced protein (sestrin), putative
— OG6
LbrM.11.0970
eukaryotic release factor 3, putative
— OG6
LbrM.25.0920
hypothetical protein, conserved
— OG6
LbrM.35.3050 ⚠
pre-mRNA splicing factor ATP-dependent RNA he
— OG6
LbrM.24.1110 ⚠
pre-mRNA-splicing factor ATP-dependent RNA he
— OG6
LbrM.16.0320
Met-10+ like-protein, putative
— OG6
LbrM.22.0770
hypothetical protein, conserved
— OG6
LbrM.27.2230 ⚠
ribonucleoside-diphosphate reductase small ch
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.