LbrM.14.1140

hypothetical protein, conserved
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_147036 OG7: OG7_0042945 70 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 70 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.19.0080 ⚠
proteasome alpha 7 subunit, putative
— Both
LbrM.27.1370 ⚠
T-complex protein 1, beta subunit, putative
— OG7
LbrM.35.7280 ⚠
T-complex protein 1, theta subunit, putative
— OG7
LbrM.13.1120 ⚠
AAA domain/Dpy-30 motif containing protein, p
— OG7
LbrM.33.0320 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LbrM.19.1110 ⚠
ABC transport system ATP-binding protein, put
— OG7
LbrM.08.0540 ⚠
ribose-phosphate pyrophosphokinase, putative
— OG7
LbrM.13.0070 ⚠
mitochondrial DNA polymerase I protein B, put
— OG7
LbrM.03.0880 ⚠
MORN repeat, putative
— OG7
LbrM.13.1520 ⚠
chaperonin TCP20, putative
— OG7
LbrM.12.0040 ⚠
proteasome beta-1 subunit, putative
— Both
LbrM.26.0030
brix domain containing-like protein
— Both
LbrM.32.3560 ⚠
chaperonin alpha subunit, putative
— Both
LbrM.28.1010
oxidoreductase-like protein
— Both
LbrM.13.1490 ⚠
mitochondrial DNA polymerase I protein D, put
— Both
LbrM.08.0900 ⚠
phosphoribosylpyrophosphate synthetase
— Both
LbrM.28.0120
proteasome beta 3 subunit, putative
— Both
LbrM.06.0800
lipin, putative
— Both
LbrM.33.0890 ⚠
proteasome subunit alpha type-5, putative
— OG7
LbrM.20.4990 ⚠
vesicular-fusion protein nsf, putative
— OG7
LbrM.28.0820 ⚠
kinetoplast poly(A) polymerase 1
— OG7
LbrM.20.3690 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
LbrM.14.0930 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
LbrM.34.1640 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
LbrM.26.0410 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
LbrM.35.1840 ⚠
proteasome subunit beta type-5, putative
— OG7
LbrM.27.0200 ⚠
proteasome alpha 7 subunit, putative
— OG7
LbrM.34.4810 ⚠
proteasome alpha 1 subunit, putative
— Both
LbrM.14.0310 ⚠
proteasome alpha 3 subunit, putative
— OG7
LbrM.35.1750 ⚠
proteasome subunit alpha type-1, putative
— OG7
LbrM.12.0210 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
LbrM.27.1390 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LbrM.34.2360 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
LbrM.35.3220 ⚠
ATP-dependent RNA helicase, putative
— OG7
LbrM.34.3840 ⚠
T-complex protein 1, eta subunit, putative
— OG7
LbrM.27.2380 ⚠
thioredoxin, putative
— Both
LbrM.32.3750 ⚠
exosome-associated protein 2, putative
— Both
LbrM.26.0850
hypothetical protein, conserved
— Both
LbrM.18.0910
hypothetical protein, conserved
— Both
LbrM.33.2210 ⚠
phosphoribosyl transferase, putative, phospho
— Both
LbrM.35.5650 ⚠
phosphoribosylpyrophosphate synthetase, putat
— Both
LbrM.23.0610
hypothetical protein, conserved
— Both
LbrM.20.2660
exosome subunit rrp6p homologue, putative
— Both
LbrM.32.3240 ⚠
ATP binding protein-like protein
— Both
LbrM.22.1490 ⚠
exosome complex exonuclease RRP45 homolog, pu
— Both
LbrM.03.0590 ⚠
DEAD/DEAH box helicase, putative
— Both
LbrM.30.3050
kinesin, putative
— OG6
LbrM.33.2550
glycosyl hydrolase-like protein
— Both
LbrM.21.2010 ⚠
proteasome alpha 2 subunit, putative
— Both
LbrM.29.1550
hypothetical protein, conserved
— Both
Page 1 of 2
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.