LbrM.33.2550

glycosyl hydrolase-like protein
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_104188 OG7: OG7_0008377 141 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 141 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.01.0690 ⚠
ubiquitin activating enzyme, putative
— OG7
LbrM.22.1170 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LbrM.27.2230 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LbrM.28.1010
oxidoreductase-like protein
— Both
LbrM.30.0830 ⚠
heat shock protein grpe, co-chaperone, GrpE,
— Both
LbrM.20.5930 ⚠
amidohydrolase, putative
— Both
LbrM.30.1491 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— Both
LbrM.20.5920 ⚠
amidohydrolase, putative
— Both
LbrM.20.5910 ⚠
amidohydrolase, putative
— Both
LbrM.31.1330 ⚠
amidohydrolase, putative
— Both
LbrM.26.0030
brix domain containing-like protein
— Both
LbrM.20.4940 ⚠
conserved protein, unknown function
— Both
LbrM.20.6130 ⚠
hypothetical protein, conserved
— Both
LbrM.03.0880 ⚠
MORN repeat, putative
— OG7
LbrM.32.2360 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.3660 ⚠
geranylgeranyltransferase, putative
— OG7
LbrM.34.3160 ⚠
replication factor C, subunit 3, putative
— OG7
LbrM.17.0530 ⚠
ATPase family associated with various cellula
— OG7
LbrM.30.2590 ⚠
replication factor C, subunit 2, putative
— OG7
LbrM.20.5250 ⚠
hypothetical protein, conserved
— OG7
LbrM.27.0660 ⚠
replication factor C, subunit 4, putative
— OG7
LbrM.35.7070 ⚠
replication factor C subunit 3, putative
— OG7
LbrM.30.0820 ⚠
co-chaperone GrpE, putative
— OG7
LbrM.29.0840
hypothetical protein, conserved
— OG7
LbrM.34.5330 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.07.0290 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LbrM.30.1210 ⚠
WW domain containing protein, putative
— OG7
LbrM.16.1170 ⚠
WW domain containing protein, putative
— OG7
LbrM.13.1120 ⚠
AAA domain/Dpy-30 motif containing protein, p
— OG7
LbrM.35.2370 ⚠
ATP-dependent RNA helicase DBP2A, putative
— OG7
LbrM.32.0470 ⚠
ATP-dependent RNA helicase HEL67
— OG7
LbrM.08.0080 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
LbrM.34.3010 ⚠
ATP-dependent RNA helicase, putative
— OG7
LbrM.07.0360 ⚠
ATP-dependent RNA helicase DBP2B, putative
— OG7
LbrM.10.0140 ⚠
mitochondrial, DEAD/DEAH box helicase, putati
— OG7
LbrM.01.0190 ⚠
LSM domain containing protein, putative
— OG7
LbrM.33.3110 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
LbrM.12.0210 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
LbrM.14.0930 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
LbrM.13.0070 ⚠
mitochondrial DNA polymerase I protein B, put
— OG7
LbrM.28.0820 ⚠
kinetoplast poly(A) polymerase 1
— OG7
LbrM.23.0490 ⚠
trypanothione synthetase, putative
— OG7
LbrM.16.0030 ⚠
AAA domain containing protein, putative
— OG7
LbrM.35.1480 ⚠
adenylate kinase, putative
— OG7
LbrM.33.0320 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LbrM.06.0920 ⚠
hypothetical protein, conserved
— OG7
LbrM.32.0820 ⚠
Outer row dynein-assembly protein 7
— OG7
LbrM.35.5130 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.2400 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.35.2170 ⚠
TLD, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.