LbrM.33.3110

cysteine peptidase, Clan CA, family C51, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_115782 OG7: OG7_0010828 63 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 63 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.26.0840 ⚠
aspartate--ammonia ligase, putative, asparagi
— OG7
LbrM.30.1370 ⚠
pyridoxal kinase, putative
— OG7
LbrM.16.0010 ⚠
anti-silencing protein a-like protein
— OG7
LbrM.35.1480 ⚠
adenylate kinase, putative
— OG7
LbrM.28.2970 ⚠
heat-shock protein hsp70, putative
— OG7
LbrM.35.5830 ⚠
aminopeptidase P1, putative, metallo-peptidas
— OG7
LbrM.35.5180 ⚠
translation initiation factor 2 subunit, puta
— OG7
LbrM.11.0040 ⚠
14-3-3 protein 2, putative
— OG7
LbrM.35.3430 ⚠
14-3-3 protein 1, putative
— OG7
LbrM.31.0160 ⚠
paraflagellar rod protein 1D
— OG7
LbrM.03.0240 ⚠
long chain fatty Acyl CoA synthetase, putativ
— OG7
LbrM.06.0570 ⚠
dUTP diphosphatase, deoxyuridine triphosphata
— OG7
LbrM.01.0520 ⚠
fatty acyl CoA syntetase 1, putative
— OG7
LbrM.14.0350 ⚠
threonine synthase, putative
— OG7
LbrM.01.0560 ⚠
long-chain-fatty-acid-CoA ligase, putative
— OG7
LbrM.01.0260 ⚠
long-chain-fatty-acid-CoA ligase, putative (f
— OG7
LbrM.34.2300 ⚠
metallo-peptidase, Clan MG, Family M24, amino
— OG7
LbrM.01.0550 ⚠
long-chain-fatty-acid-CoA ligase, putative (f
— OG7
LbrM.01.0540 ⚠
long-chain-fatty-acid-CoA ligase, putative
— OG7
LbrM.29.2850 ⚠
inosine-adenosine-guanosine-nucleosidehydrola
— OG7
LbrM.04.0630 ⚠
spermidine synthase, putative
— OG7
LbrM.27.2210 ⚠
branched-chain amino acid aminotransferase, p
— OG7
LbrM.27.1990 ⚠
paraflagellar rod protein 5, putative
— OG7
LbrM.29.1830 ⚠
paraflagellar rod protein 1D, putative
— OG7
LbrM.17.0230 ⚠
cystathionine beta-synthase (fragment)
— OG7
LbrM.35.7010 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— OG7
LbrM.33.2550 ⚠
glycosyl hydrolase-like protein
— OG7
LbrM.22.1170 ⚠
ribonucleoside-diphosphate reductase small ch
— OG7
LbrM.27.2230 ⚠
ribonucleoside-diphosphate reductase small ch
— OG7
LbrM.23.0580 ⚠
acetyl-CoA synthetase, putative
— OG7
LbrM.23.0800 ⚠
acetyl-CoA synthetase, putative
— OG7
LbrM.25.1680 ⚠
KIF-1 binding protein C terminal, putative
— OG7
LbrM.24.0790 ⚠
malic enzyme, putative
— OG7
LbrM.20.0030 ⚠
malate dehydrogenase
— OG7
LbrM.20.0010 ⚠
mitochondrial malate dehydrogenase
— OG7
LbrM.20.0020 ⚠
malate dehydrogenase, putative
— OG7
LbrM.19.1020 ⚠
glycosomal malate dehydrogenase
— OG7
LbrM.28.3070 ⚠
cytosolic malate dehydrogenase
— OG7
LbrM.26.1260 ⚠
heat shock protein 70-related protein
— OG7
LbrM.26.0910 ⚠
chaperone protein-like protein, heat shock 70
— OG7
LbrM.32.1520 ⚠
RNA capping enzyme, cytoplasmic
— OG7
LbrM.01.0790 ⚠
HSP70-like protein
— OG7
LbrM.35.7100 ⚠
prolyl endopeptidase
— OG7
LbrM.10.0060 ⚠
thymidylate kinase-like protein
— OG7
LbrM.06.0320 ⚠
oligopeptidase B-like protein, serine peptida
— OG7
LbrM.35.3820 ⚠
cysteine synthase
— OG7
LbrM.09.0920 ⚠
Uncharacterised protein family (UPF0160), put
— OG7
LbrM.19.1200 ⚠
CAP-Gly domain containing protein, putative
— OG7
LbrM.18.1400 ⚠
heat shock protein 110, putative
— OG7
LbrM.09.0850 ⚠
oligopeptidase b
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.