LbrM.27.2230

ribonucleoside-diphosphate reductase small chain, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_100537 OG7: OG7_0003661 91 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 91 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.20.5910 ⚠
amidohydrolase, putative
— Both
LbrM.35.2370 ⚠
ATP-dependent RNA helicase DBP2A, putative
— OG7
LbrM.19.1790 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
LbrM.20.1520 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.17.0090 ⚠
elongation factor 1-alpha
— OG7
LbrM.11.0930 ⚠
eukaryotic release factor 3, putative (fragme
— OG7
LbrM.12.0300 ⚠
ornithine decarboxylase, putative
— Both
LbrM.20.6130 ⚠
hypothetical protein, conserved
— Both
LbrM.20.4940 ⚠
conserved protein, unknown function
— Both
LbrM.15.0090 ⚠
ATP-dependent protease ATPase subunit HslU1,
— Both
LbrM.35.7010 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— Both
LbrM.31.1330 ⚠
amidohydrolase, putative
— Both
LbrM.35.0310 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
LbrM.20.5920 ⚠
amidohydrolase, putative
— Both
LbrM.30.1491 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— Both
LbrM.20.5930 ⚠
amidohydrolase, putative
— Both
LbrM.34.2220 ⚠
ATP-dependent RNA helicase-like protein
— OG6
LbrM.35.4280 ⚠
hypothetical protein, conserved
— Both
LbrM.33.2190 ⚠
ribosome assembly protein RRB1, putative
— Both
LbrM.34.4150 ⚠
hsp70 subfamily B suppressor 1, elongation fa
— Both
LbrM.26.1240 ⚠
hypothetical protein, conserved
— Both
LbrM.34.4530 ⚠
hypothetical protein, conserved
— Both
LbrM.29.2190 ⚠
leucine-rich repeat-containing protein
— Both
LbrM.35.5130 ⚠
hypothetical protein, conserved
— OG7
LbrM.33.3110 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
LbrM.23.0490 ⚠
trypanothione synthetase, putative
— OG7
LbrM.15.1430 ⚠
glutaminyl-tRNA synthetase, putative
— OG7
LbrM.33.3140 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
LbrM.35.6760 ⚠
protein transport protein Sec23-like protein
— OG7
LbrM.19.1230 ⚠
peptidyl-prolyl cis-trans isomerase, macropha
— OG7
LbrM.26.0750 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.10.0140 ⚠
mitochondrial, DEAD/DEAH box helicase, putati
— OG7
LbrM.23.0330 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LbrM.35.4300 ⚠
regulator of chromosome condensation 1-like p
— OG7
LbrM.11.0100 ⚠
regulator of chromatin condensation, putative
— OG7
LbrM.30.3650 ⚠
hypothetical protein, conserved
— Both
LbrM.07.0360 ⚠
ATP-dependent RNA helicase DBP2B, putative
— OG7
LbrM.10.0990 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LbrM.22.1310 ⚠
fk506-binding protein 1-like protein
— OG7
LbrM.31.3070 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.17.0220 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.34.3010 ⚠
ATP-dependent RNA helicase, putative
— OG7
LbrM.08.0080 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
LbrM.32.0820 ⚠
Outer row dynein-assembly protein 7
— OG7
LbrM.35.2810 ⚠
cyclin-e binding protein 1-like protein
— OG7
LbrM.32.0470 ⚠
ATP-dependent RNA helicase HEL67
— OG7
LbrM.22.0470 ⚠
Rab-GTPase-TBC domain containing protein, put
— Both
LbrM.14.0420 ⚠
Protein of unknown function (DUF1253), putati
— Both
LbrM.30.1370 ⚠
pyridoxal kinase, putative
— Both
LbrM.30.3280 ⚠
glutamyl-tRNA synthetase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.