LbrM.17.0090

elongation factor 1-alpha
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_100227 OG7: OG7_0001444 131 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 131 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.10.0140 ⚠
mitochondrial, DEAD/DEAH box helicase, putati
— OG7
LbrM.13.0690 ⚠
hypothetical protein, conserved
— OG7
LbrM.31.3070 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.22.1310 ⚠
fk506-binding protein 1-like protein
— OG7
LbrM.10.0990 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LbrM.29.2190 ⚠
leucine-rich repeat-containing protein
— OG7
LbrM.34.4530 ⚠
hypothetical protein, conserved
— OG7
LbrM.11.0410 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LbrM.27.2230 ⚠
ribonucleoside-diphosphate reductase small ch
— OG7
LbrM.35.4280 ⚠
hypothetical protein, conserved
— OG7
LbrM.11.0100 ⚠
regulator of chromatin condensation, putative
— OG7
LbrM.12.0300 ⚠
ornithine decarboxylase, putative
— OG7
LbrM.29.1320 ⚠
Hsp70 protein/TPR repeat, putative
— OG7
LbrM.35.4300 ⚠
regulator of chromosome condensation 1-like p
— OG7
LbrM.29.0070 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LbrM.23.0330 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LbrM.26.0750 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.19.1230 ⚠
peptidyl-prolyl cis-trans isomerase, macropha
— OG7
LbrM.35.5860 ⚠
adenylyl cyclase-associated protein, putative
— OG7
LbrM.35.2650 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.3650 ⚠
hypothetical protein, conserved
— OG7
LbrM.03.0180 ⚠
hypothetical protein
— OG7
LbrM.26.1310 ⚠
Cupin-like domain containing protein, putativ
— OG7
LbrM.16.1490 ⚠
paraflagellar rod protein 2C
— OG7
LbrM.16.1480 ⚠
paraflagellar rod protein 2C
— OG7
LbrM.11.0800 ⚠
pyruvate phosphate dikinase, putative
— OG7
LbrM.33.3260 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.2370 ⚠
ATP-dependent RNA helicase DBP2A, putative
— OG7
LbrM.28.2270 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— OG7
LbrM.32.0470 ⚠
ATP-dependent RNA helicase HEL67
— OG7
LbrM.08.0080 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
LbrM.34.3010 ⚠
ATP-dependent RNA helicase, putative
— OG7
LbrM.07.0360 ⚠
ATP-dependent RNA helicase DBP2B, putative
— OG7
LbrM.18.1400 ⚠
heat shock protein 110, putative
— OG7
LbrM.26.0910 ⚠
chaperone protein-like protein, heat shock 70
— OG7
LbrM.01.0790 ⚠
HSP70-like protein
— OG7
LbrM.01.0740 ⚠
Eukaryotic initiation factor 4A-1
— OG7
LbrM.20.3610 ⚠
nucleolar protein family a member-like protei
— OG7
LbrM.21.1700 ⚠
ATP-dependent RNA helicase SUB2, putative
— OG7
LbrM.30.1510 ⚠
WD domain, G-beta repeat, putative
— OG7
LbrM.28.1700 ⚠
ATP-dependent RNA helicase FAL1, putative
— OG7
LbrM.34.4680 ⚠
Hsp70 protein, putative
— OG7
LbrM.15.1420 ⚠
mismatch repair protein MSH3, putative
— OG7
LbrM.33.2190 ⚠
ribosome assembly protein RRB1, putative
— OG7
LbrM.02.0360 ⚠
Soluble NSF attachment protein, SNAP, putativ
— OG7
LbrM.35.2160 ⚠
DNA mismatch repair protein MSH6, putative
— OG7
LbrM.26.1240 ⚠
hypothetical protein, conserved
— OG7
LbrM.32.0820 ⚠
Outer row dynein-assembly protein 7
— OG7
LbrM.10.0330 ⚠
protein transport protein SEC23, putative
— OG7
LbrM.35.5130 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.