LbrM.35.2650

hypothetical protein, conserved
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_147016 OG7: OG7_0017902 76 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 76 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.12.0300
ornithine decarboxylase, putative
— Both
LbrM.08.0340 ⚠
Isochorismatase family, putative
— OG7
LbrM.35.0270 ⚠
elongation factor 2
— OG7
LbrM.35.0250 ⚠
elongation factor 2
— OG7
LbrM.35.0260 ⚠
elongation factor 2
— OG7
LbrM.32.2420 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
LbrM.07.0800 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.4150 ⚠
hsp70 subfamily B suppressor 1, elongation fa
— OG7
LbrM.17.0090 ⚠
elongation factor 1-alpha
— OG7
LbrM.11.0930 ⚠
eukaryotic release factor 3, putative (fragme
— OG7
LbrM.12.0080 ⚠
ribonuclease mar1
— OG7
LbrM.25.0360
translation initiation factor SUI1, putative
— Both
LbrM.15.0090 ⚠
ATP-dependent protease ATPase subunit HslU1,
— Both
LbrM.25.0970
hypothetical protein, conserved
— OG6
LbrM.27.2130
small nuclear ribonucleoprotein protein, puta
— Both
LbrM.27.2230 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LbrM.22.1170 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LbrM.02.0360
Soluble NSF attachment protein, SNAP, putativ
— Both
LbrM.14.1240
EAP30/Vps36 family, putative
— Both
LbrM.25.0910 ⚠
dehydrogenase-like protein
— OG7
LbrM.23.0330 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LbrM.33.0210 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
LbrM.03.0590 ⚠
DEAD/DEAH box helicase, putative
— OG7
LbrM.20.2430 ⚠
Carboxypeptidase-like protein
— OG7
LbrM.19.1230 ⚠
peptidyl-prolyl cis-trans isomerase, macropha
— OG7
LbrM.10.0990 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LbrM.22.1310 ⚠
fk506-binding protein 1-like protein
— OG7
LbrM.35.0310 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
LbrM.19.1790 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
LbrM.20.4740
hypothetical protein, conserved
— Both
LbrM.26.0750 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.35.4300 ⚠
regulator of chromosome condensation 1-like p
— OG7
LbrM.11.0100 ⚠
regulator of chromatin condensation, putative
— OG7
LbrM.31.3070 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.17.0220 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.35.2810 ⚠
cyclin-e binding protein 1-like protein
— OG7
LbrM.20.1520 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.08.0350 ⚠
Isochorismatase family, putative
— OG7
LbrM.25.2320
hypothetical protein, unknown function
— Both
LbrM.33.0160
hypothetical protein, conserved
— Both
LbrM.07.0100
pitrilysin-like metalloprotease, metallo-pept
— Both
LbrM.09.0230 ⚠
ATP-dependent protease ATPase subunit HslU2
— Both
LbrM.08.0360 ⚠
mitochondrial associated ribonuclease, putati
— Both
LbrM.11.0410 ⚠
metallo-peptidase, Clan MF, Family M17
— +1 more Both
LbrM.11.0400 ⚠
aminopeptidase, putative, metallo-peptidase,
— +1 more Both
LbrM.29.1320 ⚠
Hsp70 protein/TPR repeat, putative
— Both
LbrM.30.3650
hypothetical protein, conserved
— Both
LbrM.16.0560
aspartate carbamoyltransferase, putative
— Both
LbrM.33.2160
hypothetical protein, conserved
— Both
LbrM.11.0800
pyruvate phosphate dikinase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.