LbrM.10.0330

protein transport protein SEC23, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_147026 OG7: OG7_0004996 147 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 147 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.27.1750 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
LbrM.34.2460 ⚠
hypothetical protein, conserved
— Both
LbrM.25.0890 ⚠
2OG-Fe(II) oxygenase superfamily, putative
— Both
LbrM.23.1880 ⚠
Surp module, putative
— Both
LbrM.18.0230 ⚠
Activator of Hsp90 ATPase, N-terminal/Activat
— Both
LbrM.29.1390 ⚠
carnitine/choline acetyltransferase, putative
— Both
LbrM.07.0990 ⚠
Domain of unknown function (DUF3437), putativ
— Both
LbrM.10.0310 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
LbrM.22.0310 ⚠
SEP domain containing protein, putative
— Both
LbrM.20.2050
protein phosphatase 2C-like protein
— OG6
LbrM.08.0470 ⚠
WD domain, G-beta repeat, putative
— Both
LbrM.35.0680 ⚠
Elongation factor G1, mitochondrial, putative
— Both
LbrM.35.4690 ⚠
mitochondrial intermediate peptidase, putativ
— Both
LbrM.30.2040 ⚠
alcohol dehydrogenase, putative
— Both
LbrM.34.1390 ⚠
choline/ethanolamine kinase, putative
— Both
LbrM.25.2310 ⚠
hypothetical protein, conserved
— Both
LbrM.18.1050 ⚠
UDP-glucose pyrophosphorylase
— Both
LbrM.35.3890 ⚠
NUDIX hydrolase 3, putative
— Both
LbrM.27.1560 ⚠
choline kinase, ethanolamine kinase, putative
— OG7
LbrM.25.1040 ⚠
protein transport protein Sec24C, putative
— OG7
LbrM.29.0230 ⚠
protein transport protein Sec24A, putative
— OG7
LbrM.22.1080 ⚠
ChaC-like protein, putative
— OG7
LbrM.29.0510 ⚠
thymine-7-hydroxylase, putative
— OG7
LbrM.22.0300 ⚠
carnitine palmitoyltransferase-like protein
— OG7
LbrM.19.1800 ⚠
choline/Carnitine o-acyltransferase-like prot
— OG7
LbrM.28.2160 ⚠
Elongation factor G 2, mitochondrial, putativ
— OG7
LbrM.20.3180 ⚠
adenosine kinase-like protein
— OG7
LbrM.27.1650 ⚠
peptidyl dipeptidase, putative, metallo-pepti
— OG7
LbrM.30.1010 ⚠
adenosine kinase, putative
— OG7
LbrM.26.1590 ⚠
metallo-peptidase, Clan MA(E), Family M3, thi
— OG7
LbrM.02.0670 ⚠
peptidyl dipeptidase, putative, metallo-pepti
— OG7
LbrM.27.2780 ⚠
metallo-peptidase, Clan MA(E), Family M3
— OG7
LbrM.27.2760 ⚠
metallo-peptidase, Clan MA(E), Family M3, pep
— OG7
LbrM.27.1640 ⚠
metallo-peptidase, Clan MA(E), Family M3, pep
— OG7
LbrM.09.0230 ⚠
ATP-dependent protease ATPase subunit HslU2
— OG7
LbrM.35.2370 ⚠
ATP-dependent RNA helicase DBP2A, putative
— OG7
LbrM.15.0340 ⚠
Ecotin-like protein
— OG7
LbrM.27.0660 ⚠
replication factor C, subunit 4, putative
— OG7
LbrM.17.0090 ⚠
elongation factor 1-alpha
— OG7
LbrM.07.0360 ⚠
ATP-dependent RNA helicase DBP2B, putative
— OG7
LbrM.35.5130 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.7070 ⚠
replication factor C subunit 3, putative
— OG7
LbrM.20.5250 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.0540 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.19.1750 ⚠
eukaryotic translation initiation factor-like
— OG7
LbrM.19.1300 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LbrM.29.0610 ⚠
hypothetical protein, conserved
— OG7
LbrM.06.0920 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.1030 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.35.3220 ⚠
ATP-dependent RNA helicase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.