LbrM.15.1420

mismatch repair protein MSH3, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_105075 OG7: OG7_0001337 19 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 19 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.24.1000 ⚠
replication factor C, subunit 1, putative
— OG7
LbrM.28.0820 ⚠
kinetoplast poly(A) polymerase 1
— OG7
LbrM.17.0090 ⚠
elongation factor 1-alpha
— OG7
LbrM.14.0930 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
LbrM.11.0930 ⚠
eukaryotic release factor 3, putative (fragme
— OG7
LbrM.11.0970 ⚠
eukaryotic release factor 3, putative
— OG7
LbrM.26.0410 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
LbrM.35.7070 ⚠
replication factor C subunit 3, putative
— OG7
LbrM.27.0660 ⚠
replication factor C, subunit 4, putative
— OG7
LbrM.20.5250 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.5170 ⚠
hypothetical protein, conserved
— Both
LbrM.30.2590 ⚠
replication factor C, subunit 2, putative
— OG7
LbrM.17.0530 ⚠
ATPase family associated with various cellula
— OG7
LbrM.34.3160 ⚠
replication factor C, subunit 3, putative
— OG7
LbrM.34.4150 ⚠
hsp70 subfamily B suppressor 1, elongation fa
— Both
LbrM.33.0400 ⚠
DNA mismatch repair protein MSH2, putative
— Both
LbrM.19.1680 ⚠
Cid1 family poly A polymerase, putative
— Both
LbrM.21.1750
NIMA-related kinase, putative
— OG6
LbrM.16.1090 ⚠
ubiquitin fold modifier protein, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.