LbrM.34.2400

ubiquitin-protein ligase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_146796 OG7: OG7_0002947 161 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 161 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.16.0400 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LbrM.32.2420 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
LbrM.35.0260 ⚠
elongation factor 2
— OG7
LbrM.35.0250 ⚠
elongation factor 2
— OG7
LbrM.35.0270 ⚠
elongation factor 2
— OG7
LbrM.30.2220 ⚠
hypothetical protein, conserved
— OG7
LbrM.23.0520 ⚠
5'-AMP-activated protein kinase subunit beta,
— OG7
LbrM.34.5330 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.07.0290 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LbrM.30.1210 ⚠
WW domain containing protein, putative
— OG7
LbrM.16.1170 ⚠
WW domain containing protein, putative
— OG7
LbrM.30.1030 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.18.1380 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.4270 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
LbrM.33.0210 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
LbrM.08.0340 ⚠
Isochorismatase family, putative
— OG7
LbrM.12.0080 ⚠
ribonuclease mar1
— OG7
LbrM.08.0350 ⚠
Isochorismatase family, putative
— OG7
LbrM.26.1390 ⚠
GTP-binding protein-like protein, guanine nuc
— OG7
LbrM.34.5160 ⚠
hypothetical protein, conserved
— OG7
LbrM.33.2680 ⚠
ras-like small GTPases, putative
— OG7
LbrM.05.0470 ⚠
GTPase, putative
— OG7
LbrM.23.0340 ⚠
hypothetical protein, conserved
— OG7
LbrM.01.0190 ⚠
LSM domain containing protein, putative
— OG7
LbrM.01.0690 ⚠
ubiquitin activating enzyme, putative
— OG7
LbrM.26.0760 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.26.0020 ⚠
Lsm7p protein, putative
— OG7
LbrM.08.0230 ⚠
ubiquitin-activating enzyme-like protein (fra
— OG7
LbrM.32.1170 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LbrM.34.4440 ⚠
sm-f snRNP core complex protein, putative
— OG7
LbrM.25.2290 ⚠
LSM domain containing protein, putative
— OG7
LbrM.35.2810 ⚠
cyclin-e binding protein 1-like protein
— OG7
LbrM.30.1330 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LbrM.17.0220 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.31.3070 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.11.0100 ⚠
regulator of chromatin condensation, putative
— OG7
LbrM.35.4300 ⚠
regulator of chromosome condensation 1-like p
— OG7
LbrM.26.0750 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.34.1640 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
LbrM.15.1240 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
LbrM.19.1330 ⚠
hypothetical protein, unknown function
— OG7
LbrM.03.0410 ⚠
TLD domain protein, conserved
— OG7
LbrM.26.0440 ⚠
pseudouridylate synthase-like protein
— OG7
LbrM.30.0640 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.2170 ⚠
TLD, putative
— OG7
LbrM.06.0920 ⚠
hypothetical protein, conserved
— OG7
LbrM.08.0470 ⚠
WD domain, G-beta repeat, putative
— OG7
LbrM.10.1250 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
LbrM.30.3400 ⚠
calmodulin-related protein, putative
— OG7
LbrM.30.1610 ⚠
pseudouridine synthase A-like protein, putati
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.