LbrM.08.0540

ribose-phosphate pyrophosphokinase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_145869 OG7: OG7_0002319 172 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 172 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.31.3340 ⚠
acetyl-CoA carboxylase
— +5 more Both
LbrM.08.0900 ⚠
phosphoribosylpyrophosphate synthetase
— +4 more Both
LbrM.35.5650 ⚠
phosphoribosylpyrophosphate synthetase, putat
— +5 more Both
LbrM.33.2210 ⚠
phosphoribosyl transferase, putative, phospho
— +5 more Both
LbrM.20.0330 ⚠
DNA-directed RNA polymerase III subunit C1, p
— Both
LbrM.31.2950 ⚠
RNA polymerase ii largest subunit
— Both
LbrM.16.1400 ⚠
DNA-directed rna polymerase I largest subunit
— Both
LbrM.05.1110 ⚠
DNA-directed RNA polymerase I largest subunit
— Both
LbrM.32.3560 ⚠
chaperonin alpha subunit, putative
— +2 more OG7
LbrM.20.4090 ⚠
DNA-directed RNA polymerase III, putative
— OG7
LbrM.29.0150 ⚠
DNA-directed RNA polymerase II subunit 3, put
— OG7
LbrM.06.0510 ⚠
SpoU rRNA Methylase family, putative
— OG7
LbrM.24.2370 ⚠
cullin-like protein-like protein
— OG7
LbrM.16.1260 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LbrM.34.5330 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.02.0130 ⚠
phosphatidylinositol kinase related protein,
— OG7
LbrM.11.0790 ⚠
adaptin-related protein-like protein
— OG7
LbrM.19.1260 ⚠
FYVE zinc finger, putative
— OG7
LbrM.31.0270 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
LbrM.18.0660 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LbrM.04.0960 ⚠
adenylate kinase, putative
— OG7
LbrM.32.3160 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
LbrM.20.5280 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LbrM.23.1810 ⚠
neutral sphingomyelinase activation associate
— OG7
LbrM.35.3280 ⚠
cullin-like protein
— OG7
LbrM.33.3060 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LbrM.20.3990 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LbrM.07.0290 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LbrM.35.2620 ⚠
Cullin protein neddylation domain containing
— OG7
LbrM.20.3550 ⚠
target of rapamycin kinase 3, putative
— OG7
LbrM.35.7120 ⚠
beta adaptin, putative
— OG7
LbrM.10.0900 ⚠
hypothetical protein, conserved
— OG7
LbrM.24.1720 ⚠
SpoU rRNA Methylase family, putative
— OG7
LbrM.28.2310 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LbrM.16.0030 ⚠
AAA domain containing protein, putative
— OG7
LbrM.14.1340 ⚠
ras-like small GTPases, putative
— OG7
LbrM.02.0170 ⚠
RNA helicase, putative (fragment)
— OG7
LbrM.32.1620 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LbrM.16.1170 ⚠
WW domain containing protein, putative
— OG7
LbrM.35.1480 ⚠
adenylate kinase, putative
— OG7
LbrM.23.1500 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LbrM.26.1280 ⚠
hypothetical protein, unknown function
— OG7
LbrM.34.4240 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.1910 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.1030 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.14.1140 ⚠
hypothetical protein, conserved
— OG7
LbrM.12.0480 ⚠
vacuolar ATP synthase subunit, putative
— OG7
LbrM.32.3750 ⚠
exosome-associated protein 2, putative
— OG7
LbrM.27.2380 ⚠
thioredoxin, putative
— OG7
LbrM.34.3440 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.