LbrM.12.0040

proteasome beta-1 subunit, putative

Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101390 OG7: OG7_0001933 55 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 55 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LbrM.27.0200 ⚠ proteasome alpha 7 subunit, putative	—	OG6 Tb927.3.780 ↔ Tb927.6.1260 OG6 LdBPK_120030.1 ↔ LdBPK_270190.1 OG7 Tb927.10.230 ↔ Tb927.10.6080 OG7 Tb927.10.290 ↔ Tb927.10.6080 +43 more	Both
LbrM.06.0120 ⚠ 20S proteasome beta 6 subunit, putative, prot	—	OG6 TCSYLVIO_002482 ↔ TCSYLVIO_006999 OG6 Tb927.6.1260 ↔ Tb927.7.4790 OG6 LdBPK_060140.1 ↔ LdBPK_120030.1 OG7 TCSYLVIO_002482 ↔ TCSYLVIO_006999 +5 more	Both
LbrM.34.4810 ⚠ proteasome alpha 1 subunit, putative	—	OG6 LdBPK_120030.1 ↔ LdBPK_354910.1 OG6 Tb927.6.1260 ↔ Tb927.9.9670 OG6 TCSYLVIO_005678 ↔ TCSYLVIO_006999 OG7 Tb927.10.230 ↔ Tb927.10.6080 +44 more	Both
LbrM.21.2010 ⚠ proteasome alpha 2 subunit, putative	—	OG6 LdBPK_120030.1 ↔ LdBPK_212070.1 OG6 Tb927.10.290 ↔ Tb927.6.1260 OG6 TCSYLVIO_006999 ↔ TCSYLVIO_009369 OG7 Tb927.10.230 ↔ Tb927.10.6080 +44 more	Both
LbrM.35.0400 ⚠ proteasome subunit beta type-2, putative	—	OG6 LdBPK_120030.1 ↔ LdBPK_360340.1 OG6 Tb927.10.4710 ↔ Tb927.6.1260 OG6 TCSYLVIO_006999 ↔ TCSYLVIO_007432 OG7 LdBPK_120030.1 ↔ LdBPK_360340.1 +5 more	Both
LbrM.34.3820 ⚠ proteasome beta 2 subunit, putative	—	OG6 LdBPK_120030.1 ↔ LdBPK_353880.1 OG6 TCSYLVIO_005774 ↔ TCSYLVIO_006999 OG7 LdBPK_120030.1 ↔ LdBPK_353880.1 OG7 LdBPK_120030.1 ↔ LdBPK_361730.1 +3 more	Both
LbrM.14.0310 ⚠ proteasome alpha 3 subunit, putative	—	OG6 LdBPK_120030.1 ↔ LdBPK_140310.1 OG6 Tb927.6.1260 ↔ Tb927.7.4420 OG6 TCSYLVIO_006999 ↔ TCSYLVIO_010341 OG7 Tb927.10.230 ↔ Tb927.10.6080 +44 more	Both
LbrM.35.1840 ⚠ proteasome subunit beta type-5, putative	—	OG6 LdBPK_120030.1 ↔ LdBPK_361730.1 OG6 Tb927.10.6080 ↔ Tb927.6.1260 OG7 LdBPK_120030.1 ↔ LdBPK_353880.1 OG7 LdBPK_120030.1 ↔ LdBPK_361730.1 +3 more	Both
LbrM.33.0890 ⚠ proteasome subunit alpha type-5, putative	—	OG6 Tb927.10.230 ↔ Tb927.6.1260 OG6 LdBPK_120030.1 ↔ LdBPK_212200.1 OG7 Tb927.10.230 ↔ Tb927.10.6080 OG7 Tb927.10.290 ↔ Tb927.10.6080 +43 more	Both
LbrM.35.1750 ⚠ proteasome subunit alpha type-1, putative	—	OG6 Tb11.v5.0196 ↔ Tb927.6.1260 OG6 Tb927.10.6030 ↔ Tb927.6.1260 OG6 LdBPK_120030.1 ↔ LdBPK_361670.1 OG6 TCSYLVIO_004937 ↔ TCSYLVIO_006999 +45 more	Both
LbrM.19.0080 ⚠ proteasome alpha 7 subunit, putative	—	OG6 LdBPK_110240.1 ↔ LdBPK_120030.1 OG6 Tb927.11.7020 ↔ Tb927.6.1260 OG6 TCSYLVIO_001707 ↔ TCSYLVIO_006999 OG7 Tb927.10.230 ↔ Tb927.10.6080 +44 more	Both
LbrM.28.0120 ⚠ proteasome beta 3 subunit, putative	—	OG6 Tb927.11.7270 ↔ Tb927.6.1260 OG6 LdBPK_120030.1 ↔ LdBPK_280110.1 OG6 TCSYLVIO_001736 ↔ TCSYLVIO_006999 OG7 LdBPK_120030.1 ↔ LdBPK_280110.1 +6 more	Both
LbrM.35.7280 ⚠ T-complex protein 1, theta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_006999 +2 more	OG7
LbrM.20.1210 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_003934 ↔ TCSYLVIO_004939	OG7
LbrM.27.1370 ⚠ T-complex protein 1, beta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_006999 +2 more	OG7
LbrM.13.1520 ⚠ chaperonin TCP20, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_006999 +2 more	OG7
LbrM.34.3840 ⚠ T-complex protein 1, eta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_006999 +2 more	OG7
LbrM.14.1140 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_006999 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010606	Both
LbrM.35.3220 ⚠ ATP-dependent RNA helicase, putative	—	OG7 TCSYLVIO_004479 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004479 ↔ TCSYLVIO_006999	OG7
LbrM.20.2350 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_003828 ↔ TCSYLVIO_004939	OG7
LbrM.29.0150 ⚠ DNA-directed RNA polymerase II subunit 3, put	—	OG7 TCSYLVIO_004939 ↔ TCSYLVIO_010718	OG7
LbrM.09.1380 ⚠ paraflagellar rod component, putative	—	OG7 TCSYLVIO_004939 ↔ TCSYLVIO_006797	OG7
LbrM.19.0980 ⚠ DNA-directed RNA polymerases I and III subuni	—	OG7 TCSYLVIO_004939 ↔ TCSYLVIO_010718	OG7
LbrM.08.0540 ⚠ ribose-phosphate pyrophosphokinase, putative	—	OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_006999	OG7
LbrM.14.0010 ⚠ ribosomal RNA processing protein 4, putative,	—	OG7 TCSYLVIO_004939 ↔ TCSYLVIO_010369	OG7
LbrM.25.0560 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_004939 ↔ TCSYLVIO_007412	OG7
LbrM.09.0120 ⚠ flagellar pocket cytoskeletal protein bilbo1	—	OG7 TCSYLVIO_004939 ↔ TCSYLVIO_006469	OG7
LbrM.24.1480 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_004939 ↔ TCSYLVIO_009798	OG7
LbrM.08.0090 ⚠ adaptor complex protein (AP) 3 delta subunit	—	OG7 TCSYLVIO_004939 ↔ TCSYLVIO_010530	OG7
LbrM.30.1400 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_003184 ↔ TCSYLVIO_004939	OG7
LbrM.01.0590 ⚠ pre-mRNA processing factor 3 (PRP3)/Protein o	—	OG7 TCSYLVIO_003433 ↔ TCSYLVIO_004939	OG7
LbrM.26.1160 ⚠ mitochondrial RNA binding complex 1 subunit,	—	OG7 TCSYLVIO_002300 ↔ TCSYLVIO_004939	OG7
LbrM.32.3060 ⚠ proteasome regulatory non-ATP-ase subunit, pu	—	OG7 Tb927.10.6080 ↔ Tb927.11.16030	OG7
LbrM.22.1490 ⚠ exosome complex exonuclease RRP45 homolog, pu	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_006999	Both
LbrM.29.1550 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_004312 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_004312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004312 ↔ TCSYLVIO_006999	Both
LbrM.20.3980 ⚠ 20s proteasome beta 7 subunit, (putative)	—	OG6 Tb927.4.430 ↔ Tb927.6.1260 OG7 Tb927.4.430 ↔ Tb927.6.1260 OG7 Tb927.10.6080 ↔ Tb927.4.430	Both
LbrM.20.3950 ⚠ 20s proteasome beta 7 subunit, (putative)	—	OG6 Tb927.4.430 ↔ Tb927.6.1260 OG7 Tb927.4.430 ↔ Tb927.6.1260 OG7 Tb927.10.6080 ↔ Tb927.4.430	Both
LbrM.03.0590 ⚠ DEAD/DEAH box helicase, putative	—	OG6 TCSYLVIO_004479 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_004479 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004479 ↔ TCSYLVIO_006999	Both
LbrM.27.2380 ⚠ thioredoxin, putative	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_006999	Both
LbrM.32.3240 ⚠ ATP binding protein-like protein	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_006999	Both
LbrM.20.2660 ⚠ exosome subunit rrp6p homologue, putative	—	OG6 TCSYLVIO_003804 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_003804 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_003804 ↔ TCSYLVIO_006999	Both
LbrM.35.5650 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_004731 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_005774 +1 more	Both
LbrM.33.2210 ⚠ phosphoribosyl transferase, putative, phospho	—	OG6 TCSYLVIO_004731 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_005774 +1 more	Both
LbrM.32.3750 ⚠ exosome-associated protein 2, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_006999	Both
LbrM.21.1320 ⚠ T-complex protein 1, delta subunit, putative	—	OG6 TCSYLVIO_006999 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_006999 +3 more	Both
LbrM.19.0060 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001704 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_001704 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_001704 ↔ TCSYLVIO_006999	Both
LbrM.32.1100 ⚠ chaperonin containing t-complex protein, puta	—	OG6 TCSYLVIO_000177 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_006999 +3 more	Both
LbrM.23.1320 ⚠ T-complex protein 1, gamma subunit, putative	—	OG6 TCSYLVIO_000177 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_006999 +3 more	Both
LbrM.03.0140 ⚠ acetyltransferase, putative	—	OG6 TCSYLVIO_004519 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_004519 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004519 ↔ TCSYLVIO_006999	Both
LbrM.20.0320 ⚠ eukaryotic translation initiation factor 5, p	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006999	Both

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