LbrM.25.0170

cleavage and polyadenylation specificity factor, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_103283 OG7: OG7_0002417 151 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 151 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.20.3010 ⚠
cleavage and polyadenylation specificity fact
— Both
LbrM.33.1670 ⚠
protein kinase
— OG7
LbrM.25.2000 ⚠
hypothetical protein, conserved
— Both
LbrM.19.1110 ⚠
ABC transport system ATP-binding protein, put
— Both
LbrM.22.1440 ⚠
alanyl-tRNA synthetase, putative
— Both
LbrM.25.0750 ⚠
protein kinase, putative
— Both
LbrM.20.5310 ⚠
Pre-mRNA-splicing factor 38, putative
— Both
LbrM.28.2560 ⚠
serine hydroxymethyltransferase (SHMT-L)
— Both
LbrM.18.0940
hypothetical protein, conserved, cyclosporin
— OG6
LbrM.14.1560 ⚠
tyrosyl-tRNA synthetase, putative
— Both
LbrM.34.2630 ⚠
acyl-CoA dehydrogenase, putative
— Both
LbrM.14.1540 ⚠
myo-inositol-1-phosphate synthase, inositol-3
— Both
LbrM.23.0120 ⚠
GDP-mannose pyrophosphorylase
— Both
LbrM.14.1490 ⚠
serine hydroxymethyltranferase (SHMT-S)
— Both
LbrM.29.0070 ⚠
tryptophanyl-tRNA synthetase, putative
— Both
LbrM.20.5870 ⚠
tRNA (Uracil-5-)-methyltransferase, putative
— Both
LbrM.21.0900 ⚠
methionyl-tRNA synthetase, putative
— Both
LbrM.14.0460 ⚠
N-terminal conserved domain of Nudc./CS domai
— Both
LbrM.25.1690 ⚠
eukaryotic translation initiation factor 3 su
— Both
LbrM.34.4530 ⚠
hypothetical protein, conserved
— Both
LbrM.35.2630 ⚠
serine peptidase, Clan SC, Family S9B
— Both
LbrM.18.0110 ⚠
alpha glucosidase II subunit, putative
— Both
LbrM.27.0470 ⚠
Nuclear pore complex protein 158
— Both
LbrM.35.0200 ⚠
PUB domain containing protein, putative
— Both
LbrM.12.0610 ⚠
TPR repeat, putative
— Both
LbrM.28.0460 ⚠
DIS3-like exonuclease, putative
— Both
LbrM.05.0790 ⚠
hypothetical protein, conserved
— Both
LbrM.24.0940 ⚠
hypothetical protein, conserved
— Both
LbrM.35.5900 ⚠
isoleucyl-tRNA synthetase, putative
— Both
LbrM.32.4220 ⚠
Gar1/Naf1 RNA binding region, putative
— Both
LbrM.03.0820 ⚠
inorganic pyrophosphatase, putative
— Both
LbrM.19.0110 ⚠
acidocalcisomal pyrophosphatase
— Both
LbrM.09.1270 ⚠
AAA family ATPase, putative
— Both
LbrM.28.0340 ⚠
rrp44p homologue, putative
— OG7
LbrM.04.0360 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LbrM.20.1420 ⚠
N-terminal region of Chorein, a TM vesicle-me
— OG7
LbrM.09.1040 ⚠
N-terminal region of Chorein, a TM vesicle-me
— OG7
LbrM.35.4340 ⚠
glycosyl hydrolase-like protein
— OG7
LbrM.34.2860 ⚠
pentatricopeptide repeat domain containing pr
— OG7
LbrM.30.0540 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.29.1160 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LbrM.33.0150 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LbrM.04.0570 ⚠
palmitoyl acyltransferase 1, putative
— OG7
LbrM.30.3300 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LbrM.28.1460 ⚠
Ankyrin repeats (3 copies)/DHHC palmitoyltran
— OG7
LbrM.34.2571 ⚠
ankyrin repeat protein, putative
— OG7
LbrM.16.1610 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.5460 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
LbrM.20.2440 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LbrM.32.4210 ⚠
cAMP response protein 1, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.