LbrM.30.1980

cysteine peptidase, Clan CA, family C2, putative, calpain-like cysteine peptidase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_146872 OG7: OG7_0001161 48 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 48 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.16.0320
Met-10+ like-protein, putative
— OG6
LbrM.26.1180
RNA pseudouridylate synthase, putative
— OG6
LbrM.27.1820
hypothetical protein, conserved
— OG6
LbrM.01.0030
DNA-damage inducible protein DDI1-like protei
— OG6
LbrM.26.0490
hypothetical protein, conserved
— OG6
LbrM.17.0960
Phosphorylated CTD interacting factor 1 WW do
— OG6
LbrM.29.2130
cdc2-related kinase 10, putative
— OG6
LbrM.30.0550
hypothetical protein, conserved
— OG6
LbrM.13.0460
hypothetical protein, conserved
— OG6
LbrM.14.1540
myo-inositol-1-phosphate synthase, inositol-3
— OG6
LbrM.25.0920
hypothetical protein, conserved
— OG6
LbrM.35.3050 ⚠
pre-mRNA splicing factor ATP-dependent RNA he
— OG6
LbrM.13.0580
C2 domain containing protein, putative
— OG6
LbrM.24.1110 ⚠
pre-mRNA-splicing factor ATP-dependent RNA he
— OG6
LbrM.34.1120 ⚠
pre-mRNA splicing factor ATP-dependent RNA he
— OG6
LbrM.20.5930 ⚠
amidohydrolase, putative
— OG6
LbrM.30.1491 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— OG6
LbrM.20.5920 ⚠
amidohydrolase, putative
— OG6
LbrM.20.5910 ⚠
amidohydrolase, putative
— OG6
LbrM.31.1330 ⚠
amidohydrolase, putative
— OG6
LbrM.25.0680
DNL zinc finger, putative
— OG6
LbrM.19.0530
polyprenyl synthase, putative
— OG6
LbrM.28.0340
rrp44p homologue, putative
— OG6
LbrM.12.0300
ornithine decarboxylase, putative
— OG6
LbrM.17.1550 ⚠
zinc-finger protein ZPR1, putative
— OG6
LbrM.15.0530
hypothetical protein, conserved
— OG6
LbrM.06.0690
hypothetical protein, conserved
— OG6
LbrM.15.0700
hypothetical protein, conserved
— OG6
LbrM.30.1590
phosphopantothenoylcysteine decarboxylase, pu
— OG6
LbrM.11.0800
pyruvate phosphate dikinase, putative
— OG6
LbrM.29.1320
Hsp70 protein/TPR repeat, putative
— OG6
LbrM.11.0400 ⚠
aminopeptidase, putative, metallo-peptidase,
— OG6
LbrM.11.0410 ⚠
metallo-peptidase, Clan MF, Family M17
— OG6
LbrM.05.0200
50S ribosome-binding GTPase, putative
— OG6
LbrM.17.1330
methyltransferase domain containing protein,
— OG6
LbrM.17.1560 ⚠
zinc-finger protein ZPR1, putative
— OG6
LbrM.24.1960
cyclin 10
— OG6
LbrM.09.0830
acyl-CoA binding protein, putative
— OG6
LbrM.33.2840
metallo-peptidase, Clan MF, Family M17
— OG6
LbrM.33.1670
protein kinase
— OG6
LbrM.14.1240
EAP30/Vps36 family, putative
— OG6
LbrM.35.6540
flagellum transition zone component, putative
— OG6
LbrM.31.1630
hypothetical protein, conserved
— OG6
LbrM.20.1180
hypothetical protein, conserved
— OG6
LbrM.30.3060
tRNA (Guanine-1)-methyltransferase, putative
— OG6
LbrM.34.4530
hypothetical protein, conserved
— OG6
LbrM.34.2220
ATP-dependent RNA helicase-like protein
— OG6
LbrM.29.2720
hypothetical protein, conserved
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.