LbrM.06.0690

hypothetical protein, conserved
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_146710 OG7: OG7_0052299 72 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 72 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.05.0200 ⚠
50S ribosome-binding GTPase, putative
— Both
LbrM.17.0630 ⚠
Acyl CoA binding protein, putative
— OG7
LbrM.19.1790 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
LbrM.28.0460 ⚠
DIS3-like exonuclease, putative
— OG7
LbrM.05.0470 ⚠
GTPase, putative
— OG7
LbrM.33.2680 ⚠
ras-like small GTPases, putative
— OG7
LbrM.34.5160 ⚠
hypothetical protein, conserved
— OG7
LbrM.26.1390 ⚠
GTP-binding protein-like protein, guanine nuc
— OG7
LbrM.01.0030
DNA-damage inducible protein DDI1-like protei
— Both
LbrM.04.0360 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LbrM.34.2220
ATP-dependent RNA helicase-like protein
— OG6
LbrM.30.0550
hypothetical protein, conserved
— Both
LbrM.25.0920
hypothetical protein, conserved
— Both
LbrM.30.1590
phosphopantothenoylcysteine decarboxylase, pu
— Both
LbrM.11.0410 ⚠
metallo-peptidase, Clan MF, Family M17
— +1 more Both
LbrM.34.4530
hypothetical protein, conserved
— Both
LbrM.27.1820 ⚠
hypothetical protein, conserved
— Both
LbrM.30.3060
tRNA (Guanine-1)-methyltransferase, putative
— Both
LbrM.04.0290 ⚠
RNA pseudouridylate synthase-like protein
— OG7
LbrM.30.3660 ⚠
CYC2-like protein, putative
— OG7
LbrM.19.1230 ⚠
peptidyl-prolyl cis-trans isomerase, macropha
— OG7
LbrM.03.0070 ⚠
Met-10+ like-protein, putative
— OG7
LbrM.17.0610 ⚠
Acyl CoA binding protein, putative
— OG7
LbrM.27.1830 ⚠
mRNA export factor MEX67
— OG7
LbrM.33.0820 ⚠
G1 cyclin CycE4, putative
— OG7
LbrM.10.0990 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LbrM.22.1310 ⚠
fk506-binding protein 1-like protein
— OG7
LbrM.16.0320 ⚠
Met-10+ like-protein, putative
— Both
LbrM.05.0890 ⚠
CYC2-like cyclin, putative
— OG7
LbrM.24.1950 ⚠
cyclin 11, putative
— OG7
LbrM.15.0400 ⚠
RNA pseudouridylate synthase, putative
— OG7
LbrM.25.0750 ⚠
protein kinase, putative
— OG7
LbrM.29.2030 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.2160 ⚠
acyl-CoA binding protein, putative
— OG7
LbrM.32.0910 ⚠
CYC2-like cyclin, putative
— OG7
LbrM.35.0310 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
LbrM.24.1110 ⚠
pre-mRNA-splicing factor ATP-dependent RNA he
— OG6
LbrM.11.0800
pyruvate phosphate dikinase, putative
— Both
LbrM.13.0460 ⚠
hypothetical protein, conserved
— Both
LbrM.19.0530
polyprenyl synthase, putative
— Both
LbrM.29.2720
hypothetical protein, conserved
— Both
LbrM.30.1491 ⚠
N-acyl-L-amino acid amidohydrolase, putative
— Both
LbrM.35.6540
flagellum transition zone component, putative
— Both
LbrM.15.0700
hypothetical protein, conserved
— Both
LbrM.17.1330
methyltransferase domain containing protein,
— Both
LbrM.09.0830 ⚠
acyl-CoA binding protein, putative
— Both
LbrM.14.1240
EAP30/Vps36 family, putative
— Both
LbrM.11.0400 ⚠
aminopeptidase, putative, metallo-peptidase,
— +1 more Both
LbrM.33.1670 ⚠
protein kinase
— Both
LbrM.29.2130
cdc2-related kinase 10, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.