LbrM.20.3130

Programmed cell death protein 2, C-terminal putative domain containing protein, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_136955 OG7: OG7_0004545 84 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 84 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.07.0100 ⚠
pitrilysin-like metalloprotease, metallo-pept
— OG7
LbrM.04.0570 ⚠
palmitoyl acyltransferase 1, putative
— OG7
LbrM.31.2160 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LbrM.30.0600 ⚠
N-acetyltransferase B complex (NatB) non cata
— OG7
LbrM.33.3330 ⚠
tyrosyl-DNA phosphodiesterase, putative
— OG7
LbrM.20.1170 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LbrM.17.0330 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LbrM.31.2280 ⚠
succinyl-diaminopimelate desuccinylase-like p
— OG7
LbrM.33.2100 ⚠
peptidase M20/M25/M40, putative
— OG7
LbrM.34.2571 ⚠
ankyrin repeat protein, putative
— OG7
LbrM.28.1460 ⚠
Ankyrin repeats (3 copies)/DHHC palmitoyltran
— OG7
LbrM.30.3300 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LbrM.28.1990 ⚠
Replication factor A protein 1
— OG7
LbrM.33.0150 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LbrM.18.1200 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LbrM.29.1160 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LbrM.26.0590 ⚠
Protein of unknown function (DUF525), putativ
— OG7
LbrM.34.2250 ⚠
hypothetical protein, conserved
— OG7
LbrM.03.0510 ⚠
kinase-like protein
— OG7
LbrM.15.1110 ⚠
hypothetical protein, conserved
— OG7
LbrM.11.0610 ⚠
hypothetical protein, conserved
— OG7
LbrM.11.0170 ⚠
hypothetical protein, conserved
— OG7
LbrM.31.2100 ⚠
peptidase m20/m25/m40 family-like protein
— OG7
LbrM.18.1100 ⚠
5-oxoprolinase, putative
— OG7
LbrM.24.1360 ⚠
WD domain, G-beta repeat, putative
— OG7
LbrM.13.0370 ⚠
Uncharacterized ACR, COG1678, putative
— OG7
LbrM.32.1960 ⚠
hypothetical protein, conserved
— OG7
LbrM.25.2260 ⚠
hypothetical protein, conserved
— OG7
LbrM.04.1210 ⚠
tRNA nucleotidyltransferase, putative
— OG7
LbrM.30.3480 ⚠
DNA ligase I, putative
— OG7
LbrM.31.2120 ⚠
peptidase m20/m25/m40 family-like protein
— OG7
LbrM.26.2010 ⚠
hypothetical protein, unknown function
— OG7
LbrM.28.2200 ⚠
hypothetical protein, conserved
— OG7
LbrM.03.0650 ⚠
TatD related DNase, putative
— OG7
LbrM.23.0700 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LbrM.30.1920 ⚠
C2H2 type zinc-finger (2 copies), putative
— OG7
LbrM.34.2970 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LbrM.27.0930 ⚠
WD domain, G-beta repeat, putative
— OG7
LbrM.33.1880 ⚠
cytosolic nonspecific dipeptidase, putative
— OG7
LbrM.35.0560 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LbrM.22.1030 ⚠
Beta-lactamase superfamily domain containing
— OG7
LbrM.22.1020 ⚠
Beta-lactamase superfamily domain containing
— OG7
LbrM.26.2000 ⚠
hypothetical protein, conserved
— OG7
LbrM.18.0240 ⚠
RNA-binding protein 29, putative
— OG7
LbrM.18.0390 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LbrM.08.0340 ⚠
Isochorismatase family, putative
— OG7
LbrM.11.0490 ⚠
anion-transporting ATPase-like protein
— OG7
LbrM.13.0680 ⚠
metallo-peptidase, Clan ME, Family M16, mitoc
— OG7
LbrM.21.0400 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LbrM.33.2890 ⚠
Mitochondrial-processing peptidase subunit al
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.