LbrM.25.2260

hypothetical protein, conserved
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_158193 OG7: OG7_0052300 107 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 107 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.16.0090 ⚠
Galactose oxidase, central domain/Domain of u
— OG7
LbrM.35.2490 ⚠
developmentally regulated GTP-binding protein
— Both
LbrM.34.3830 ⚠
30S Ribosomal protein S17-like protein
— Both
LbrM.33.2890 ⚠
Mitochondrial-processing peptidase subunit al
— Both
LbrM.20.5810 ⚠
ribosomal protein S11 homolog
— Both
LbrM.21.1680 ⚠
40S ribosomal protein S11, putative
— Both
LbrM.28.1270
AN1-like zinc finger, putative
— Both
LbrM.20.0460
calcium channel protein, putative, ion transp
— Both
LbrM.35.6500
Sucrase/ferredoxin-like, putative
— Both
LbrM.22.0930 ⚠
hypothetical protein, conserved
— Both
LbrM.34.4260 ⚠
Spindle assembly abnormal protein 6 homolog
— Both
LbrM.25.2210
hypothetical protein SCD6.10
— Both
LbrM.23.0650 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LbrM.35.6680 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LbrM.11.1140
tRNA pseudouridine synthase D (TruD), putativ
— Both
LbrM.29.1160 ⚠
Ankyrin repeats (3 copies), putative
— Both
LbrM.33.0430
hypothetical protein, conserved
— Both
LbrM.34.2980
hypothetical protein, conserved
— Both
LbrM.28.0460 ⚠
DIS3-like exonuclease, putative
— OG7
LbrM.04.0360 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LbrM.18.1140 ⚠
cholinephosphate cytidylyltransferase A, puta
— OG7
LbrM.34.5250 ⚠
ribosome-interacting GTPase 2, putative
— OG7
LbrM.21.0400 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LbrM.13.0680 ⚠
metallo-peptidase, Clan ME, Family M16, mitoc
— OG7
LbrM.28.1760 ⚠
Galactose oxidase, central domain containing
— OG7
LbrM.24.2170 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LbrM.28.2350 ⚠
hypothetical protein, conserved
— OG7
LbrM.18.1200 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LbrM.05.0470 ⚠
GTPase, putative
— OG7
LbrM.33.2680 ⚠
ras-like small GTPases, putative
— OG7
LbrM.26.1390 ⚠
GTP-binding protein-like protein, guanine nuc
— OG7
LbrM.05.0200 ⚠
50S ribosome-binding GTPase, putative
— OG7
LbrM.04.0140
hypothetical protein, conserved
— OG7
LbrM.32.2890 ⚠
SpoU rRNA Methylase family, putative
— OG7
LbrM.20.3130 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LbrM.06.0510 ⚠
SpoU rRNA Methylase family, putative
— OG7
LbrM.34.2571 ⚠
ankyrin repeat protein, putative
— OG7
LbrM.28.1460 ⚠
Ankyrin repeats (3 copies)/DHHC palmitoyltran
— OG7
LbrM.30.3300 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LbrM.04.0570 ⚠
palmitoyl acyltransferase 1, putative
— OG7
LbrM.33.0150 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LbrM.35.7000 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.4400 ⚠
kelch domain-containing protein
— OG7
LbrM.35.1610 ⚠
kelch motif containing protein, putative
— OG7
LbrM.24.0490 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LbrM.35.6491 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.2290 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LbrM.19.0770
hypothetical protein, conserved
— OG7
LbrM.34.1010 ⚠
hypothetical protein, unknown function
— OG7
LbrM.34.1030 ⚠
zinc finger CCCH domain containing protein 11
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.