LbrM.28.2990

heat-shock protein hsp70, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_100083 OG7: OG7_0000779 234 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 234 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.18.1400 ⚠
heat shock protein 110, putative
— +3 more Both
LbrM.26.0910 ⚠
chaperone protein-like protein, heat shock 70
— +2 more OG7
LbrM.01.0790 ⚠
HSP70-like protein
— +2 more OG7
LbrM.26.1260 ⚠
heat shock protein 70-related protein
— +7 more Both
LbrM.28.3030 ⚠
heat shock protein 70, putative
— +1 more OG6
LbrM.28.2980 ⚠
heat-shock protein hsp70, putative (fragment)
— +7 more Both
LbrM.28.2970 ⚠
heat-shock protein hsp70, putative
— +7 more Both
LbrM.28.1300 ⚠
luminal binding protein 1 (BiP), putative
— +7 more Both
LbrM.30.2420 ⚠
heat shock 70-related protein 1, mitochondria
— +8 more Both
LbrM.18.0610 ⚠
hypothetical protein, conserved
— Both
LbrM.30.2450 ⚠
heat shock 70-related protein 1, mitochondria
— +8 more Both
LbrM.34.4680 ⚠
Hsp70 protein, putative
— +2 more OG7
LbrM.30.2500 ⚠
heat shock 70-related protein 1, mitochondria
— +8 more Both
LbrM.30.2440 ⚠
heat shock 70-related protein 1, mitochondria
— +8 more Both
LbrM.30.2410 ⚠
heat shock 70-related protein 1, mitochondria
— +8 more Both
LbrM.30.2430 ⚠
heat shock 70-related protein 1, mitochondria
— +8 more Both
LbrM.22.0080 ⚠
heat shock protein DNAJ, putative
— OG7
LbrM.35.0830 ⚠
Protein C21orf2 homolog, putative
— OG7
LbrM.27.2610 ⚠
heat shock protein DNAJ, putative
— OG7
LbrM.35.2340 ⚠
chaperone protein DnaJ, putative
— OG7
LbrM.15.1170 ⚠
DnaJ domain/DnaJ central domain containing pr
— OG7
LbrM.19.1420 ⚠
hypothetical protein, conserved
— OG7
LbrM.32.3590 ⚠
chaperone protein DnaJ, putative
— OG7
LbrM.31.2390 ⚠
hypothetical protein, conserved
— OG7
LbrM.33.1090 ⚠
dnaj chaperone-like protein
— OG7
LbrM.23.0340 ⚠
hypothetical protein, conserved
— OG7
LbrM.12.0210 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
LbrM.10.0140 ⚠
mitochondrial, DEAD/DEAH box helicase, putati
— OG7
LbrM.32.3160 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
LbrM.07.0360 ⚠
ATP-dependent RNA helicase DBP2B, putative
— OG7
LbrM.34.3010 ⚠
ATP-dependent RNA helicase, putative
— OG7
LbrM.08.0080 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
LbrM.27.1390 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LbrM.34.2360 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
LbrM.33.0330 ⚠
heat shock protein 83-1
— OG7
LbrM.28.2270 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— OG7
LbrM.33.0340 ⚠
heat shock protein 83, heat shock protein 83-
— OG7
LbrM.29.0780 ⚠
heat shock protein 90, putative
— OG7
LbrM.22.0090 ⚠
cap guanylyltransferase-methyltransferase 1
— OG7
LbrM.35.2370 ⚠
ATP-dependent RNA helicase DBP2A, putative
— OG7
LbrM.33.0350 ⚠
heat shock protein 83-1
— OG7
LbrM.30.1510 ⚠
WD domain, G-beta repeat, putative
— OG7
LbrM.23.0490 ⚠
trypanothione synthetase, putative
— OG7
LbrM.33.3140 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
LbrM.31.2810 ⚠
uridine kinase-like protein
— OG7
LbrM.31.2760 ⚠
uridine kinase-like protein
— OG7
LbrM.20.1010 ⚠
uracil phosphoribosyltransferase, putative
— OG7
LbrM.30.2790 ⚠
chaperonin HSP60/CNP60, putative
— OG7
LbrM.35.5140 ⚠
exosome-associated protein 4, putative
— OG7
LbrM.15.1080 ⚠
Peroxiredoxin PRX1A
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.