LbrM.20.1740

Glycosyl hydrolase family 65 central catalytic domain/Glycosyl hydrolase family 65, C-terminal domain containing protein, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_143485 OG7: OG7_0042752 122 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 122 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.31.1440
Protein of unknown function (DUF3638)/Protein
— Both
LbrM.35.5490
glycosyl hydrolase, putative
— Both
LbrM.18.0910
hypothetical protein, conserved
— +2 more Both
LbrM.20.0330 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
LbrM.33.0320 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LbrM.16.0070 ⚠
peroxisome assembly protein, putative
— OG7
LbrM.35.6620 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LbrM.02.0130 ⚠
phosphatidylinositol kinase related protein,
— OG7
LbrM.11.0790 ⚠
adaptin-related protein-like protein
— OG7
LbrM.20.5280 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LbrM.20.3990 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LbrM.20.3550 ⚠
target of rapamycin kinase 3, putative
— OG7
LbrM.35.7120 ⚠
beta adaptin, putative
— OG7
LbrM.32.1620 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LbrM.20.4090 ⚠
DNA-directed RNA polymerase III, putative
— OG7
LbrM.31.0270 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
LbrM.35.5650 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LbrM.08.0900 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LbrM.33.2210 ⚠
phosphoribosyl transferase, putative, phospho
— OG7
LbrM.04.1230 ⚠
casein kinase I, putative
— OG7
LbrM.20.2600 ⚠
protein kinase, putative
— OG7
LbrM.30.3520 ⚠
casein kinase 1 isoform 2, putative
— OG7
LbrM.34.0990 ⚠
casein kinase I, putative
— OG7
LbrM.27.1900 ⚠
casein kinase I-like protein
— OG7
LbrM.25.2430 ⚠
casein kinase I, putative
— OG7
LbrM.10.0900
hypothetical protein, conserved
— OG7
LbrM.24.2370 ⚠
cullin-like protein-like protein
— OG7
LbrM.16.1260 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LbrM.35.3280 ⚠
cullin-like protein
— OG7
LbrM.35.2620 ⚠
Cullin protein neddylation domain containing
— OG7
LbrM.28.2310 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LbrM.23.1810 ⚠
neutral sphingomyelinase activation associate
— OG7
LbrM.33.3060 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LbrM.34.4240 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.6491 ⚠
hypothetical protein, conserved
— OG7
LbrM.24.0490 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LbrM.35.1610 ⚠
kelch motif containing protein, putative
— OG7
LbrM.20.4400 ⚠
kelch domain-containing protein
— OG7
LbrM.16.0090 ⚠
Galactose oxidase, central domain/Domain of u
— OG7
LbrM.28.2350 ⚠
hypothetical protein, conserved
— OG7
LbrM.22.0930 ⚠
hypothetical protein, conserved
— OG7
LbrM.24.2170 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LbrM.28.1760 ⚠
Galactose oxidase, central domain containing
— OG7
LbrM.24.1720 ⚠
SpoU rRNA Methylase family, putative
— OG7
LbrM.06.0510 ⚠
SpoU rRNA Methylase family, putative
— OG7
LbrM.34.3440 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LbrM.21.1570 ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LbrM.05.0410 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LbrM.32.1520 ⚠
RNA capping enzyme, cytoplasmic
— OG7
LbrM.23.1500 ⚠
DNA polymerase theta (helicase domain only),
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.