LbrM.13.0900

leucyl-tRNA synthetase, putative

Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101014 OG7: OG7_0005523 101 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 101 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LbrM.21.0900 methionyl-tRNA synthetase, putative	—	OG6 Tb927.10.1500 ↔ Tb927.11.3730 OG6 TCSYLVIO_003028 ↔ TCSYLVIO_007991 OG7 Tb927.10.1500 ↔ Tb927.11.3730 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_007991	Both
LbrM.35.5900 isoleucyl-tRNA synthetase, putative	—	OG6 Tb927.10.9190 ↔ Tb927.11.3730 OG6 TCSYLVIO_003028 ↔ TCSYLVIO_004705 OG7 Tb927.10.9190 ↔ Tb927.11.3730 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_004705	Both
LbrM.30.3120 valyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_003345 OG6 Tb927.11.3730 ↔ Tb927.6.4480 OG7 Tb927.11.3730 ↔ Tb927.6.4480 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_003345	Both
LbrM.14.1560 ⚠ tyrosyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_010624 OG6 Tb927.11.3730 ↔ Tb927.7.3620 OG7 Tb927.11.3730 ↔ Tb927.7.3620 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_010624	Both
LbrM.29.0070 ⚠ tryptophanyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_010724 OG6 Tb927.11.3730 ↔ Tb927.3.5580 OG7 Tb927.11.3730 ↔ Tb927.3.5580 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_010724	Both
LbrM.35.4070 glycyl tRNA synthetase, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_009222 OG6 Tb927.11.3730 ↔ Tb927.11.9640 OG7 Tb927.11.3730 ↔ Tb927.11.9640 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_009222	Both
LbrM.22.0420 ⚠ Putative tRNA binding domain containing prote	—	OG7 Tb927.11.3730 ↔ Tb927.7.3620 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_010624	OG7
LbrM.16.1160 ⚠ tyrosyl or methionyl-tRNA synthetase-like pro	—	OG7 Tb927.11.3730 ↔ Tb927.7.3620 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_010624	OG7
LbrM.23.0330 ⚠ tryptophanyl-tRNA synthetase, putative	—	OG7 Tb927.11.3730 ↔ Tb927.3.5580 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_010724	OG7
LbrM.24.1190 hypothetical protein, conserved	—	OG6 TCSYLVIO_001462 ↔ TCSYLVIO_003028 OG7 TCSYLVIO_001462 ↔ TCSYLVIO_003028	Both
LbrM.15.0040 Possible lysine decarboxylase, putative	—	OG6 TCSYLVIO_002403 ↔ TCSYLVIO_003028 OG7 TCSYLVIO_002403 ↔ TCSYLVIO_003028	Both
LbrM.06.0870 ⚠ acyl-coenzyme a dehydrogenase, putative	—	OG6 TCSYLVIO_001861 ↔ TCSYLVIO_003028 OG7 TCSYLVIO_001861 ↔ TCSYLVIO_003028	Both
LbrM.06.0850 ⚠ acyl-coenzyme a dehydrogenase, putative	—	OG6 TCSYLVIO_001861 ↔ TCSYLVIO_003028 OG7 TCSYLVIO_001861 ↔ TCSYLVIO_003028	Both
LbrM.31.3470 ⚠ metallopeptidase, putative	—	OG6 TCSYLVIO_002764 ↔ TCSYLVIO_003028 OG7 TCSYLVIO_002764 ↔ TCSYLVIO_003028	Both
LbrM.31.3520 ⚠ metallo-peptidase, Clan ME, Family M16	—	OG6 TCSYLVIO_002764 ↔ TCSYLVIO_003028 OG7 TCSYLVIO_002764 ↔ TCSYLVIO_003028	Both
LbrM.31.3350 hypothetical protein, conserved	—	OG6 TCSYLVIO_002771 ↔ TCSYLVIO_003028 OG7 TCSYLVIO_002771 ↔ TCSYLVIO_003028	Both
LbrM.22.0140 hypothetical protein, conserved	—	OG6 TCSYLVIO_001150 ↔ TCSYLVIO_003028 OG7 TCSYLVIO_001150 ↔ TCSYLVIO_003028	Both
LbrM.35.0120 ⚠ stress-inducible protein STI1 homolog	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_003496	OG6
LbrM.30.1240 importin alpha, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_003173 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_003173	Both
LbrM.20.1840 ⚠ asparaginyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_003867 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_003867	Both
LbrM.25.0170 ⚠ cleavage and polyadenylation specificity fact	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_005414 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_005414	Both
LbrM.06.0320 ⚠ oligopeptidase B-like protein, serine peptida	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_006546 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_006546	Both
LbrM.34.3170 Peroxin 19	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_005818 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_005818	Both
LbrM.17.0330 ⚠ dihydrouridine synthase (Dus), putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_009102 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_009102	Both
LbrM.25.2000 hypothetical protein, conserved	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_010323 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_010323	Both
LbrM.09.0850 ⚠ oligopeptidase b	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_006546 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_006546	Both
LbrM.19.1110 ⚠ ABC transport system ATP-binding protein, put	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_006012 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_006012	Both
LbrM.34.0420 hypothetical protein, conserved	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_005084 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_005084	Both
LbrM.25.0750 ⚠ protein kinase, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_007401 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_007401	Both
LbrM.20.5310 Pre-mRNA-splicing factor 38, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_007337 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_007337	Both
LbrM.27.0360 protein kinase, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_005149	OG6
LbrM.03.0210 delta-1-pyrroline-5-carboxylate dehydrogenase	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_004515 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_004515	Both
LbrM.28.2560 ⚠ serine hydroxymethyltransferase (SHMT-L)	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_010621 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_010621	Both
LbrM.18.0940 hypothetical protein, conserved, cyclosporin	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_006217	OG6
LbrM.30.0690 nitrate reductase, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_003124	OG6
LbrM.20.4450 ⚠ deoxyhypusine synthase, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_003028 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_007258	Both
LbrM.34.2630 acyl-CoA dehydrogenase, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_005872 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_005872	Both
LbrM.14.1540 myo-inositol-1-phosphate synthase, inositol-3	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_007453	Both
LbrM.23.0120 GDP-mannose pyrophosphorylase	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_007603 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_007603	Both
LbrM.14.1490 ⚠ serine hydroxymethyltranferase (SHMT-S)	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_010621 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_010621	Both
LbrM.20.5870 tRNA (Uracil-5-)-methyltransferase, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_008409 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_008409	Both
LbrM.30.3340 UV excision repair RAD23-like protein	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_003361 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_003361	Both
LbrM.30.0710 histidyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_003126 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_003126	Both
LbrM.30.3460 T-complex protein 11, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_003373 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_003373	Both
LbrM.20.0300 ⚠ deoxyhypusine synthase, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_003028 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_007258	Both
LbrM.30.3480 DNA ligase I, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_003375 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_003375	Both
LbrM.34.0390 hypothetical protein, conserved	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_005080 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_005080	Both
LbrM.14.0460 ⚠ N-terminal conserved domain of Nudc./CS domai	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_010327 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_010327	Both
LbrM.27.2600 ⚠ TPR-repeat protein, putative	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_003496	OG6
LbrM.20.3350 hypothetical protein, conserved	—	OG6 TCSYLVIO_003028 ↔ TCSYLVIO_003737 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_003737	Both

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