LbrM.13.0900

leucyl-tRNA synthetase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101014 OG7: OG7_0005523 101 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 101 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.21.0900
methionyl-tRNA synthetase, putative
— Both
LbrM.35.5900
isoleucyl-tRNA synthetase, putative
— Both
LbrM.30.3120
valyl-tRNA synthetase, putative
— Both
LbrM.14.1560 ⚠
tyrosyl-tRNA synthetase, putative
— Both
LbrM.29.0070 ⚠
tryptophanyl-tRNA synthetase, putative
— Both
LbrM.35.4070
glycyl tRNA synthetase, putative
— Both
LbrM.22.0420 ⚠
Putative tRNA binding domain containing prote
— OG7
LbrM.16.1160 ⚠
tyrosyl or methionyl-tRNA synthetase-like pro
— OG7
LbrM.23.0330 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LbrM.24.1190
hypothetical protein, conserved
— Both
LbrM.15.0040
Possible lysine decarboxylase, putative
— Both
LbrM.06.0870 ⚠
acyl-coenzyme a dehydrogenase, putative
— Both
LbrM.06.0850 ⚠
acyl-coenzyme a dehydrogenase, putative
— Both
LbrM.31.3470 ⚠
metallopeptidase, putative
— Both
LbrM.31.3520 ⚠
metallo-peptidase, Clan ME, Family M16
— Both
LbrM.31.3350
hypothetical protein, conserved
— Both
LbrM.22.0140
hypothetical protein, conserved
— Both
LbrM.35.0120 ⚠
stress-inducible protein STI1 homolog
— OG6
LbrM.30.1240
importin alpha, putative
— Both
LbrM.20.1840 ⚠
asparaginyl-tRNA synthetase, putative
— Both
LbrM.25.0170 ⚠
cleavage and polyadenylation specificity fact
— Both
LbrM.06.0320 ⚠
oligopeptidase B-like protein, serine peptida
— Both
LbrM.34.3170
Peroxin 19
— Both
LbrM.17.0330 ⚠
dihydrouridine synthase (Dus), putative
— Both
LbrM.25.2000
hypothetical protein, conserved
— Both
LbrM.09.0850 ⚠
oligopeptidase b
— Both
LbrM.19.1110 ⚠
ABC transport system ATP-binding protein, put
— Both
LbrM.34.0420
hypothetical protein, conserved
— Both
LbrM.25.0750 ⚠
protein kinase, putative
— Both
LbrM.20.5310
Pre-mRNA-splicing factor 38, putative
— Both
LbrM.27.0360
protein kinase, putative
— OG6
LbrM.03.0210
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
LbrM.28.2560 ⚠
serine hydroxymethyltransferase (SHMT-L)
— Both
LbrM.18.0940
hypothetical protein, conserved, cyclosporin
— OG6
LbrM.30.0690
nitrate reductase, putative
— OG6
LbrM.20.4450 ⚠
deoxyhypusine synthase, putative
— Both
LbrM.34.2630
acyl-CoA dehydrogenase, putative
— Both
LbrM.14.1540
myo-inositol-1-phosphate synthase, inositol-3
— Both
LbrM.23.0120
GDP-mannose pyrophosphorylase
— Both
LbrM.14.1490 ⚠
serine hydroxymethyltranferase (SHMT-S)
— Both
LbrM.20.5870
tRNA (Uracil-5-)-methyltransferase, putative
— Both
LbrM.30.3340
UV excision repair RAD23-like protein
— Both
LbrM.30.0710
histidyl-tRNA synthetase, putative
— Both
LbrM.30.3460
T-complex protein 11, putative
— Both
LbrM.20.0300 ⚠
deoxyhypusine synthase, putative
— Both
LbrM.30.3480
DNA ligase I, putative
— Both
LbrM.34.0390
hypothetical protein, conserved
— Both
LbrM.14.0460 ⚠
N-terminal conserved domain of Nudc./CS domai
— Both
LbrM.27.2600 ⚠
TPR-repeat protein, putative
— OG6
LbrM.20.3350
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.