LbrM.35.4150

S-adenosylhomocysteine hydrolase
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_100715 OG7: OG7_0003269 52 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 52 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.25.0630 ⚠
protein phosphatase, putative
— OG6
LbrM.06.0350 ⚠
glutamine synthetase, putative
— Both
LbrM.23.0120 ⚠
GDP-mannose pyrophosphorylase
— Both
LbrM.34.3140 ⚠
cystathione gamma lyase, putative
— Both
LbrM.26.0050 ⚠
glycine dehydrogenase, putative
— Both
LbrM.23.0050 ⚠
Peroxiredoxin PRX1M
— Both
LbrM.14.0470 ⚠
cystathionine beta-lyase-like protein
— Both
LbrM.15.1430 ⚠
glutaminyl-tRNA synthetase, putative
— Both
LbrM.33.2590 ⚠
udp-glc 4'-epimerase, putative
— Both
LbrM.05.0950 ⚠
3-mercaptopyruvate sulfurtransferase (fragmen
— Both
LbrM.05.0970 ⚠
3-mercaptopyruvate sulfurtransferase
— Both
LbrM.03.0210 ⚠
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
LbrM.33.2890 ⚠
Mitochondrial-processing peptidase subunit al
— Both
LbrM.15.1050 ⚠
glutamate dehydrogenase
— Both
LbrM.35.2580 ⚠
tyrosine aminotransferase
— Both
LbrM.21.0400 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LbrM.13.0680 ⚠
metallo-peptidase, Clan ME, Family M16, mitoc
— OG7
LbrM.15.1140 ⚠
protein kinase, putative
— OG7
LbrM.32.4210 ⚠
cAMP response protein 1, putative
— OG7
LbrM.20.2440 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LbrM.35.5650 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LbrM.08.0540 ⚠
ribose-phosphate pyrophosphokinase, putative
— OG7
LbrM.30.3280 ⚠
glutamyl-tRNA synthetase, putative
— OG7
LbrM.33.2210 ⚠
phosphoribosyl transferase, putative, phospho
— OG7
LbrM.35.4690 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
LbrM.27.0930 ⚠
WD domain, G-beta repeat, putative
— OG7
LbrM.27.1640 ⚠
metallo-peptidase, Clan MA(E), Family M3, pep
— Both
LbrM.17.0230 ⚠
cystathionine beta-synthase (fragment)
— Both
LbrM.30.0690 ⚠
nitrate reductase, putative
— OG6
LbrM.19.1710 ⚠
mitogen-activated protein kinase 4
— OG6
LbrM.04.0010 ⚠
phosphoacetylglucosamine mutase-like gene
— Both
LbrM.33.1650 ⚠
mitogen activated protein kinase, putative
— OG6
LbrM.35.1950 ⚠
aldehyde dehydrogenase, putative
— Both
LbrM.02.0040 ⚠
aminopeptidase P1, putative, metallo-peptidas
— Both
LbrM.25.2020 ⚠
Xaa-Pro aminopeptidase, putative
— Both
LbrM.35.3320 ⚠
ATP synthase, putative
— Both
LbrM.27.1650 ⚠
peptidyl dipeptidase, putative, metallo-pepti
— Both
LbrM.26.1590 ⚠
metallo-peptidase, Clan MA(E), Family M3, thi
— Both
LbrM.27.2760 ⚠
metallo-peptidase, Clan MA(E), Family M3, pep
— Both
LbrM.35.3820 ⚠
cysteine synthase
— OG6
LbrM.02.0670 ⚠
peptidyl dipeptidase, putative, metallo-pepti
— Both
LbrM.27.2780 ⚠
metallo-peptidase, Clan MA(E), Family M3
— Both
LbrM.11.0800 ⚠
pyruvate phosphate dikinase, putative
— Both
LbrM.28.2630 ⚠
Vacuolar proton pump subunit B, putative
— Both
LbrM.13.0150 ⚠
protein kinase A regulatory subunit
— Both
LbrM.14.1540 ⚠
myo-inositol-1-phosphate synthase, inositol-3
— Both
LbrM.20.0160 ⚠
glucose-6-phosphate 1-dehydrogenase, putative
— Both
LbrM.08.0900 ⚠
phosphoribosylpyrophosphate synthetase
— Both
LbrM.20.3260 ⚠
vacuolar ATP synthase catalytic subunit A, pu
— Both
LbrM.23.0370 ⚠
(H+)-ATPase G subunit, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.