LbrM.30.1800

microtubule associated protein xmap215
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101795 OG7: OG7_0005125 87 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 87 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.29.1790 ⚠
MORN repeat, putative
— Both
LbrM.21.1990 ⚠
pumillio protein 3, putative
— OG7
LbrM.18.1450 ⚠
pumilio protein, putative, pumilio protein 2,
— OG7
LbrM.20.5610 ⚠
RNA-binding regulatory protein, putative, pum
— OG7
LbrM.10.0191 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.5580 ⚠
pumilio protein, putative, RNA-binding regula
— OG7
LbrM.20.3660 ⚠
geranylgeranyltransferase, putative
— OG7
LbrM.33.2840 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LbrM.18.1100
5-oxoprolinase, putative
— Both
LbrM.23.1570
Inositol hexakisphosphate, putative
— Both
LbrM.28.2080
p21-C-terminal region-binding protein, putati
— Both
LbrM.06.0050 ⚠
pumilio/PUF RNA binding protein 5, putative
— OG7
LbrM.02.0360
Soluble NSF attachment protein, SNAP, putativ
— Both
LbrM.08.0470
WD domain, G-beta repeat, putative
— Both
LbrM.11.0690
hypothetical protein, conserved
— Both
LbrM.22.0060 ⚠
transcription factor-like protein
— Both
LbrM.11.0720
Short C-terminal domain/PUB domain containing
— Both
LbrM.11.0810
inositol-1,4,5-trisphosphate (IP3) 5-phosphat
— Both
LbrM.18.1310
bifunctional aminoacyl-tRNA synthetase, putat
— Both
LbrM.28.0880 ⚠
RNA binding protein rbp16, putative
— Both
LbrM.10.0630
hypothetical protein, conserved
— Both
LbrM.06.0760
Double RNA binding domain protein 12
— Both
LbrM.34.3430 ⚠
zinc finger protein, putative
— OG7
LbrM.31.1570 ⚠
'Cold-shock' DNA-binding domain containing pr
— OG7
LbrM.17.0240
hypothetical protein, conserved
— OG7
LbrM.30.2790 ⚠
chaperonin HSP60/CNP60, putative
— OG7
LbrM.04.1100
hypothetical protein, conserved
— OG7
LbrM.35.3220 ⚠
ATP-dependent RNA helicase, putative
— OG7
LbrM.34.4240 ⚠
hypothetical protein, conserved
— OG7
LbrM.26.1280 ⚠
hypothetical protein, unknown function
— OG7
LbrM.14.1340 ⚠
ras-like small GTPases, putative
— OG7
LbrM.26.1440 ⚠
FYVE zinc finger, putative
— OG7
LbrM.19.1260 ⚠
FYVE zinc finger, putative
— OG7
LbrM.18.1220
AN1-like zinc finger, putative
— Both
LbrM.29.0610 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.1910 ⚠
hypothetical protein, conserved
— OG7
LbrM.23.0130 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LbrM.23.1810 ⚠
neutral sphingomyelinase activation associate
— OG7
LbrM.31.0420 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LbrM.30.0540 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.31.0480 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LbrM.21.1130 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.33.1360 ⚠
pumilio protein 6, putative
— OG7
LbrM.35.0090 ⚠
PUF1, putative
— OG7
LbrM.33.3020
translation initiation factor IF-2, putative
— Both
LbrM.17.0790 ⚠
GMP reductase
— OG6
LbrM.19.1820 ⚠
inosine-5'-monophosphate dehydrogenase
— Both
LbrM.09.0550
leucine-rich repeat protein, putative
— Both
LbrM.11.0410 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
LbrM.11.0400 ⚠
aminopeptidase, putative, metallo-peptidase,
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.