LbrM.32.3910

3-hydroxyisobutyryl-coenzyme a hydrolase-like protein
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_138999 OG7: OG7_0000750 133 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 133 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.16.0750 ⚠
transaldolase, putative
— OG7
LbrM.28.1440 ⚠
hypothetical protein, conserved
— OG7
LbrM.32.2280 ⚠
cytidylyltransferase, putative
— OG7
LbrM.26.1230 ⚠
aldo/keto reductase family-like protein, aldo
— OG7
LbrM.31.3240 ⚠
aldehyde reductase, putative, oxidoreductase,
— OG7
LbrM.27.2620 ⚠
aldo-keto reductase-like protein
— OG7
LbrM.33.0770 ⚠
WD domain, G-beta repeat, putative
— OG7
LbrM.01.0740 ⚠
Eukaryotic initiation factor 4A-1
— OG7
LbrM.21.1700 ⚠
ATP-dependent RNA helicase SUB2, putative
— OG7
LbrM.28.1700 ⚠
ATP-dependent RNA helicase FAL1, putative
— OG7
LbrM.23.1720 ⚠
alanine racemase, putative
— OG7
LbrM.20.3600 ⚠
AP-1 adapter complex gamma subunit, putative
— OG7
LbrM.07.0050 ⚠
alpha-adaptin-like protein
— OG7
LbrM.26.2300 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LbrM.32.1050 ⚠
ubiquitin-conjugating enzyme protein, putativ
— OG7
LbrM.32.1750 ⚠
phosphomannose isomerase
— OG7
LbrM.20.3180 ⚠
adenosine kinase-like protein
— OG7
LbrM.30.1010 ⚠
adenosine kinase, putative
— OG7
LbrM.25.1710 ⚠
succinyl-CoA synthetase alpha subunit, putati
— OG7
LbrM.25.1700 ⚠
succinyl-CoA synthetase alpha subunit, putati
— OG7
LbrM.32.1000 ⚠
Alpha/beta hydrolase family, putative
— OG7
LbrM.31.0140 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LbrM.29.1390 ⚠
carnitine/choline acetyltransferase, putative
— OG7
LbrM.22.0300 ⚠
carnitine palmitoyltransferase-like protein
— OG7
LbrM.19.1800 ⚠
choline/Carnitine o-acyltransferase-like prot
— OG7
LbrM.32.2630 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.3380 ⚠
phosphomannomutase-like protein
— OG7
LbrM.28.1530 ⚠
hypothetical protein, conserved
— OG7
LbrM.28.1520 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LbrM.21.1000 ⚠
xanthine phosphoribosyltransferase
— OG7
LbrM.21.0990 ⚠
hypoxanthine-guanine phosphoribosyltransferas
— OG7
LbrM.25.0910 ⚠
dehydrogenase-like protein
— OG7
LbrM.28.1490 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LbrM.28.1510 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LbrM.28.1190 ⚠
WD domain, G-beta repeat, putative
— OG7
LbrM.03.0480 ⚠
quinone oxidoreductase, putative
— OG7
LbrM.16.1390 ⚠
hypothetical protein, conserved
— OG7
LbrM.33.1160 ⚠
nicotinate phosphoribosyltransferase, putativ
— OG7
LbrM.35.3170 ⚠
succinyl-CoA ligase [GDP-forming] beta-chain,
— OG7
LbrM.03.0660 ⚠
hypothetical protein, conserved
— OG7
LbrM.31.1820 ⚠
diphthine synthase-like protein
— OG7
LbrM.34.0810 ⚠
aspartate aminotransferase, putative
— OG7
LbrM.24.0370 ⚠
aspartate aminotransferase, putative
— OG7
LbrM.26.0350 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG7
LbrM.24.0200 ⚠
transcription elongation factor, putative
— OG7
LbrM.33.3090 ⚠
transcription elongation factor-like protein
— OG7
LbrM.35.7010 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— OG7
LbrM.17.1380 ⚠
hypothetical protein, conserved
— OG7
LbrM.01.0240 ⚠
CUE domain/Domain of unknown function (DUF177
— OG7
LbrM.26.1840 ⚠
deoxyhypusine hydroxylase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.