LbrM.26.2300

SPRY domain/HECT-domain (ubiquitin-transferase), putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_146743 OG7: OG7_0043053 205 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 205 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.20.0770 ⚠
elongation factor 1-beta
— Both
LbrM.27.2620 ⚠
aldo-keto reductase-like protein
— OG7
LbrM.31.3240 ⚠
aldehyde reductase, putative, oxidoreductase,
— OG7
LbrM.10.1490
hypothetical protein, conserved
— OG7
LbrM.13.1470 ⚠
Kinesin-13 5, putative
— OG7
LbrM.01.0060 ⚠
Kinesin-13 1, putative
— OG7
LbrM.31.0400 ⚠
Kinesin-13 4, putative
— OG7
LbrM.13.0120 ⚠
Kinesin-13 2, putative
— OG7
LbrM.04.0940
hypothetical protein, conserved
— Both
LbrM.19.0110 ⚠
acidocalcisomal pyrophosphatase
— Both
LbrM.03.0820 ⚠
inorganic pyrophosphatase, putative
— Both
LbrM.35.7360
eukaryotic translation initiation factor 3 su
— Both
LbrM.34.0610
hypothetical protein, conserved
— Both
LbrM.20.0750 ⚠
elongation factor 1-beta
— Both
LbrM.20.0840
hypothetical protein, conserved
— Both
LbrM.32.1230 ⚠
hypothetical protein, conserved (fragment)
— Both
LbrM.33.2910 ⚠
dynein intermediate chain, putative
— Both
LbrM.35.5070
WD domain, G-beta repeat, putative
— Both
LbrM.31.1200
hypothetical protein, conserved
— Both
LbrM.30.3050
kinesin, putative
— OG6
LbrM.33.2540
hypothetical protein, conserved
— Both
LbrM.32.1280 ⚠
hypothetical protein, conserved
— Both
LbrM.32.3090
CS domain/TPR repeat/Tetratricopeptide repeat
— Both
LbrM.34.2330
hypothetical protein, unknown function
— Both
LbrM.20.0970 ⚠
myosin IB heavy chain, putative
— Both
LbrM.35.7340
elks delta-like protein, hypothetical protein
— Both
LbrM.33.1160
nicotinate phosphoribosyltransferase, putativ
— Both
LbrM.18.0310 ⚠
dephospho-CoA kinase, putative
— Both
LbrM.23.1720
alanine racemase, putative
— Both
LbrM.22.0310
SEP domain containing protein, putative
— Both
LbrM.28.1220
electron-transfer-flavoprotein, alpha polypep
— Both
LbrM.21.2160
hypothetical protein, conserved
— Both
LbrM.24.1070
AKAP7 2'5' RNA ligase-like domain containing
— Both
LbrM.14.1620
hypothetical protein, conserved
— Both
LbrM.20.3380
phosphomannomutase-like protein
— Both
LbrM.15.0710
hypothetical protein, conserved
— Both
LbrM.28.2260
tRNA threonylcarbamoyl adenosine modification
— Both
LbrM.01.0250
cyclophilin 12, putative
— OG6
LbrM.31.0140
ubiquitin carboxyl-terminal hydrolase, putati
— Both
LbrM.29.1170
hypothetical protein, conserved
— Both
LbrM.30.3030
eukaryotic translation initiation factor 3 su
— Both
LbrM.28.2830
Coatomer subunit gamma
— Both
LbrM.20.0810 ⚠
translation elongation factor 1-beta, putativ
— Both
LbrM.20.3040
hypothetical protein, conserved
— Both
LbrM.35.1570 ⚠
translation elongation factor 1-beta, putativ
— Both
LbrM.20.3930
coatomer alpha subunit, putative
— Both
LbrM.27.2640
hypothetical protein, conserved
— Both
LbrM.33.3090 ⚠
transcription elongation factor-like protein
— Both
LbrM.25.2400
Eukaryotic translation initiation factor 3 su
— Both
LbrM.20.3600 ⚠
AP-1 adapter complex gamma subunit, putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.