LbrM.10.1490

hypothetical protein, conserved
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_173730 OG7: OG7_0052186 120 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 120 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.18.0310 ⚠
dephospho-CoA kinase, putative
— OG7
LbrM.31.1280
biotin/lipoate protein ligase-like protein
— OG7
LbrM.18.1050
UDP-glucose pyrophosphorylase
— OG7
LbrM.34.0070 ⚠
pyruvate kinase, putative (fragment)
— OG7
LbrM.25.1580
hypothetical protein, conserved
— OG7
LbrM.25.0910 ⚠
dehydrogenase-like protein
— OG7
LbrM.34.4160 ⚠
Protein of unknown function (DUF2009), putati
— OG7
LbrM.19.1800 ⚠
choline/Carnitine o-acyltransferase-like prot
— OG7
LbrM.31.1820
diphthine synthase-like protein
— OG7
LbrM.17.1380 ⚠
hypothetical protein, conserved
— OG7
LbrM.06.0520 ⚠
U-box domain containing protein, putative
— OG7
LbrM.26.2630 ⚠
6-phosphogluconolactonase
— OG7
LbrM.34.0060 ⚠
pyruvate kinase
— OG7
LbrM.32.1050
ubiquitin-conjugating enzyme protein, putativ
— OG7
LbrM.13.1470 ⚠
Kinesin-13 5, putative
— OG7
LbrM.16.0750
transaldolase, putative
— OG7
LbrM.23.1720
alanine racemase, putative
— OG7
LbrM.34.0040 ⚠
pyruvate kinase
— OG7
LbrM.32.2690 ⚠
Cid1 family poly A polymerase, putative
— OG7
LbrM.35.0650 ⚠
ubiquitin-like protein, putative
— OG7
LbrM.25.1070
TAP42-like family, putative
— OG7
LbrM.30.0180 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— OG7
LbrM.25.1250
NPL4 family, putative
— OG7
LbrM.26.0350
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG7
LbrM.34.0810 ⚠
aspartate aminotransferase, putative
— OG7
LbrM.27.2620 ⚠
aldo-keto reductase-like protein
— OG7
LbrM.10.0310
isocitrate dehydrogenase [NADP], mitochondria
— OG7
LbrM.35.1020 ⚠
SNF1-related protein kinases, putative
— OG7
LbrM.35.0680 ⚠
Elongation factor G1, mitochondrial, putative
— OG7
LbrM.20.4840 ⚠
hypothetical protein, conserved
— OG7
LbrM.19.1750 ⚠
eukaryotic translation initiation factor-like
— OG7
LbrM.35.7010
2,3-bisphosphoglycerate-independent phosphogl
— OG7
LbrM.30.0530 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
LbrM.32.2280 ⚠
cytidylyltransferase, putative
— OG7
LbrM.35.3810 ⚠
Protein of unknown function (DUF2009), putati
— OG7
LbrM.28.1190
WD domain, G-beta repeat, putative
— OG7
LbrM.31.3170 ⚠
KH domain/Domain of unknown function (DUF1771
— OG7
LbrM.07.0050 ⚠
alpha-adaptin-like protein
— OG7
LbrM.29.2080 ⚠
Present in the outer mitochondrial membrane p
— OG7
LbrM.32.1000
Alpha/beta hydrolase family, putative
— OG7
LbrM.18.0030
mevalonate-diphosphate decarboxylase, putativ
— OG7
LbrM.32.0130
N-myristoyl transferase, putative
— OG7
LbrM.24.0370 ⚠
aspartate aminotransferase, putative
— OG7
LbrM.24.0650 ⚠
Kinesin-13 3, putative
— OG7
LbrM.28.1480 ⚠
hypothetical protein, conserved
— OG7
LbrM.33.1980 ⚠
protein kinase, putative
— OG7
LbrM.26.2660 ⚠
6-phosphogluconolactonase
— OG7
LbrM.16.1550
hypothetical protein, conserved
— OG7
LbrM.19.0110 ⚠
acidocalcisomal pyrophosphatase
— OG7
LbrM.34.4450 ⚠
Co-chaperone protein P23
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.