LbrM.30.0180

2-hydroxy-3-oxopropionate reductase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101839 OG7: OG7_0002731 223 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 223 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.13.0550 ⚠
ubiquitin-like protein
— Both
LbrM.35.0650 ⚠
ubiquitin-like protein, putative
— OG7
LbrM.27.0800 ⚠
UBA/TS-N domain containing protein, putative
— Both
LbrM.13.1470 ⚠
Kinesin-13 5, putative
— OG7
LbrM.34.3520 ⚠
hypothetical protein, conserved (fragment)
— OG7
LbrM.28.2160 ⚠
Elongation factor G 2, mitochondrial, putativ
— OG7
LbrM.28.1530 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.3510 ⚠
Enoyl-CoA hydratase/isomerase family/2-enoyl-
— OG7
LbrM.33.2780 ⚠
Mitochondrial SSU ribosomal protein, putative
— OG7
LbrM.27.1110 ⚠
hypothetical protein, conserved
— OG7
LbrM.03.0070 ⚠
Met-10+ like-protein, putative
— OG7
LbrM.21.1910 ⚠
mitochondrial RNA binding complex 1 subunit,
— OG7
LbrM.35.0270 ⚠
elongation factor 2
— OG7
LbrM.35.0250 ⚠
elongation factor 2
— OG7
LbrM.35.0260 ⚠
elongation factor 2
— OG7
LbrM.32.2420 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
LbrM.27.2620 ⚠
aldo-keto reductase-like protein
— OG7
LbrM.31.3240 ⚠
aldehyde reductase, putative, oxidoreductase,
— OG7
LbrM.27.2040 ⚠
hypothetical protein, conserved
— OG7
LbrM.10.1490 ⚠
hypothetical protein, conserved
— OG7
LbrM.03.0230 ⚠
hypothetical protein, conserved
— OG7
LbrM.04.0090 ⚠
hypothetical protein, conserved
— OG7
LbrM.15.0330 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.3420 ⚠
hypothetical protein, conserved
— OG7
LbrM.05.0830 ⚠
hypothetical protein, conserved
— OG7
LbrM.16.0170 ⚠
50S ribosomal protein L17, putative
— OG7
LbrM.26.2190 ⚠
hypothetical protein, conserved
— OG7
LbrM.08.0870 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.2630 ⚠
hypothetical protein, conserved
— OG7
LbrM.13.0130 ⚠
hypothetical protein, conserved
— OG7
LbrM.23.1720 ⚠
alanine racemase, putative
— Both
LbrM.34.2250 ⚠
hypothetical protein, conserved
— Both
LbrM.20.3840 ⚠
hypothetical protein, conserved
— Both
LbrM.35.4270 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— Both
LbrM.34.2280 ⚠
Importin 1
— Both
LbrM.33.0160 ⚠
hypothetical protein, conserved
— Both
LbrM.34.2970 ⚠
ubiquitin-activating enzyme E1, putative
— Both
LbrM.34.0740 ⚠
proteasome activator protein pa26, putative
— Both
LbrM.14.0880 ⚠
glutathione synthetase, putative
— Both
LbrM.28.1520 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
LbrM.24.0370 ⚠
aspartate aminotransferase, putative
— Both
LbrM.34.0810 ⚠
aspartate aminotransferase, putative
— Both
LbrM.28.1190 ⚠
WD domain, G-beta repeat, putative
— Both
LbrM.28.1220 ⚠
electron-transfer-flavoprotein, alpha polypep
— Both
LbrM.31.0400 ⚠
Kinesin-13 4, putative
— OG7
LbrM.28.0530 ⚠
hypothetical protein, conserved
— Both
LbrM.33.3090 ⚠
transcription elongation factor-like protein
— Both
LbrM.13.0120 ⚠
Kinesin-13 2, putative
— OG7
LbrM.31.0140 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
LbrM.01.0060 ⚠
Kinesin-13 1, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.