LbrM.28.0530

hypothetical protein, conserved
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_104592 OG7: OG7_0004617 23 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 23 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.34.3520 ⚠
hypothetical protein, conserved (fragment)
— OG7
LbrM.04.0120 ⚠
hypothetical protein, conserved
— OG7
LbrM.31.1880 ⚠
MYND finger, putative
— OG7
LbrM.31.1870 ⚠
MYND finger, putative
— OG7
LbrM.25.0910 ⚠
dehydrogenase-like protein
— OG7
LbrM.34.3490 ⚠
CRAL/TRIO, N-terminal domain/CRAL/TRIO domain
— OG7
LbrM.31.2330 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LbrM.31.2310 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LbrM.31.2320 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LbrM.35.3660 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LbrM.32.1430 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LbrM.32.1410 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
LbrM.05.1100 ⚠
methyltransferase domain containing protein,
— Both
LbrM.32.1420 ⚠
hypothetical protein, conserved
— Both
LbrM.35.3770
Domain of unknown function (DUF3846)/TPR repe
— OG6
LbrM.09.0680 ⚠
cyclin 1
— Both
LbrM.30.0180 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— Both
LbrM.03.0890 ⚠
eukaryotic translation initiation factor 2 su
— Both
LbrM.20.4890 ⚠
serine/threonine protein phosphatase 2A regul
— Both
LbrM.26.1840 ⚠
deoxyhypusine hydroxylase, putative
— Both
LbrM.30.1010 ⚠
adenosine kinase, putative
— Both
LbrM.20.3180 ⚠
adenosine kinase-like protein
— Both
LbrM.21.0700 ⚠
phosphoglucomutase, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.