LbrM.32.1750

phosphomannose isomerase
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_102059 OG7: OG7_0006704 165 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 165 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.21.0210 ⚠
serine/threonine-protein kinase-like protein
— OG7
LbrM.26.1230 ⚠
aldo/keto reductase family-like protein, aldo
— Both
LbrM.24.0650 ⚠
Kinesin-13 3, putative
— Both
LbrM.16.1390
hypothetical protein, conserved
— Both
LbrM.31.0730
amino acid transporter aATP11, putative
— OG6
LbrM.30.2550 ⚠
formate--tetrahydrofolate ligase
— OG6
LbrM.26.0350 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— Both
LbrM.30.0740
pdz domain containing protein, putative
— Both
LbrM.22.0110
GMP synthase [glutamine-hydrolysing]
— Both
LbrM.16.0750
transaldolase, putative
— Both
LbrM.32.2630
hypothetical protein, conserved
— Both
LbrM.35.1980 ⚠
5'-3' exoribonuclease D, putative
— Both
LbrM.06.0240 ⚠
5'-3' exoribonuclease A, putative
— Both
LbrM.34.2460
hypothetical protein, conserved
— Both
LbrM.25.0890 ⚠
2OG-Fe(II) oxygenase superfamily, putative
— Both
LbrM.30.2560
RNA-binding protein, putative
— OG6
LbrM.28.1520 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
LbrM.24.0370 ⚠
aspartate aminotransferase, putative
— Both
LbrM.34.0810 ⚠
aspartate aminotransferase, putative
— Both
LbrM.32.2280 ⚠
cytidylyltransferase, putative
— Both
LbrM.28.1190
WD domain, G-beta repeat, putative
— Both
LbrM.18.0310 ⚠
dephospho-CoA kinase, putative
— Both
LbrM.28.1220
electron-transfer-flavoprotein, alpha polypep
— Both
LbrM.23.1720
alanine racemase, putative
— Both
LbrM.22.0310
SEP domain containing protein, putative
— Both
LbrM.20.2050
protein phosphatase 2C-like protein
— OG6
LbrM.20.3380
phosphomannomutase-like protein
— Both
LbrM.28.2260
tRNA threonylcarbamoyl adenosine modification
— Both
LbrM.01.0250
cyclophilin 12, putative
— OG6
LbrM.31.0140
ubiquitin carboxyl-terminal hydrolase, putati
— Both
LbrM.33.3090 ⚠
transcription elongation factor-like protein
— Both
LbrM.13.0120 ⚠
Kinesin-13 2, putative
— OG7
LbrM.31.0400 ⚠
Kinesin-13 4, putative
— OG7
LbrM.01.0060 ⚠
Kinesin-13 1, putative
— OG7
LbrM.13.1470 ⚠
Kinesin-13 5, putative
— OG7
LbrM.10.1490
hypothetical protein, conserved
— OG7
LbrM.31.3240 ⚠
aldehyde reductase, putative, oxidoreductase,
— OG7
LbrM.27.2620 ⚠
aldo-keto reductase-like protein
— OG7
LbrM.22.1080
ChaC-like protein, putative
— OG7
LbrM.20.3600 ⚠
AP-1 adapter complex gamma subunit, putative
— OG7
LbrM.07.0050 ⚠
alpha-adaptin-like protein
— OG7
LbrM.28.2160 ⚠
Elongation factor G 2, mitochondrial, putativ
— OG7
LbrM.27.1640 ⚠
metallo-peptidase, Clan MA(E), Family M3, pep
— OG7
LbrM.28.1490 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LbrM.28.1530 ⚠
hypothetical protein, conserved
— OG7
LbrM.29.0510 ⚠
thymine-7-hydroxylase, putative
— OG7
LbrM.30.0530 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
LbrM.35.4110 ⚠
eukaryotic translation initiation factor 3 su
— OG7
LbrM.27.2760 ⚠
metallo-peptidase, Clan MA(E), Family M3, pep
— OG7
LbrM.33.1980 ⚠
protein kinase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.