LbrM.35.1980

5'-3' exoribonuclease D, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_100417 OG7: OG7_0003221 212 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 212 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.30.0180 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— Both
LbrM.21.2050 ⚠
hypothetical protein, conserved, RNA polymera
— OG7
LbrM.21.0210 ⚠
serine/threonine-protein kinase-like protein
— OG7
LbrM.28.2160 ⚠
Elongation factor G 2, mitochondrial, putativ
— OG7
LbrM.27.2620 ⚠
aldo-keto reductase-like protein
— OG7
LbrM.31.3240 ⚠
aldehyde reductase, putative, oxidoreductase,
— OG7
LbrM.10.1490 ⚠
hypothetical protein, conserved
— OG7
LbrM.13.1470 ⚠
Kinesin-13 5, putative
— OG7
LbrM.01.0060 ⚠
Kinesin-13 1, putative
— OG7
LbrM.31.0400 ⚠
Kinesin-13 4, putative
— OG7
LbrM.13.0120 ⚠
Kinesin-13 2, putative
— OG7
LbrM.33.3090 ⚠
transcription elongation factor-like protein
— Both
LbrM.22.0310 ⚠
SEP domain containing protein, putative
— Both
LbrM.23.1720 ⚠
alanine racemase, putative
— Both
LbrM.28.1220 ⚠
electron-transfer-flavoprotein, alpha polypep
— Both
LbrM.28.1190 ⚠
WD domain, G-beta repeat, putative
— Both
LbrM.34.0810 ⚠
aspartate aminotransferase, putative
— Both
LbrM.24.0370 ⚠
aspartate aminotransferase, putative
— Both
LbrM.04.0890 ⚠
axonemal dynein light chain, putative
— Both
LbrM.02.0130 ⚠
phosphatidylinositol kinase related protein,
— Both
LbrM.30.0740 ⚠
pdz domain containing protein, putative
— Both
LbrM.18.0310 ⚠
dephospho-CoA kinase, putative
— Both
LbrM.34.4450 ⚠
Co-chaperone protein P23
— Both
LbrM.20.4840 ⚠
hypothetical protein, conserved
— Both
LbrM.35.0680 ⚠
Elongation factor G1, mitochondrial, putative
— Both
LbrM.10.0310 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
LbrM.31.0730 ⚠
amino acid transporter aATP11, putative
— OG6
LbrM.18.1050 ⚠
UDP-glucose pyrophosphorylase
— Both
LbrM.35.3810 ⚠
Protein of unknown function (DUF2009), putati
— Both
LbrM.35.0620 ⚠
protein phosphatase 2C-like protein
— OG6
LbrM.30.0990 ⚠
protein phosphatase 2C, putative (fragment)
— OG6
LbrM.35.7010 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— Both
LbrM.32.2280 ⚠
cytidylyltransferase, putative
— Both
LbrM.27.2600 ⚠
TPR-repeat protein, putative
— OG6
LbrM.18.0720 ⚠
serine/threonine kinase-like protein, putativ
— Both
LbrM.32.1750 ⚠
phosphomannose isomerase
— Both
LbrM.20.3380 ⚠
phosphomannomutase-like protein
— Both
LbrM.10.0200 ⚠
Mitogen-activated protein kinase 10, putative
— OG6
LbrM.12.0030 ⚠
PITH domain-containing protein
— Both
LbrM.31.1280 ⚠
biotin/lipoate protein ligase-like protein
— Both
LbrM.32.1860 ⚠
protein phosphatase 2C, putative
— OG6
LbrM.25.1250 ⚠
NPL4 family, putative
— Both
LbrM.25.1070 ⚠
TAP42-like family, putative
— Both
LbrM.34.0040 ⚠
pyruvate kinase
— Both
LbrM.32.1050 ⚠
ubiquitin-conjugating enzyme protein, putativ
— Both
LbrM.34.0060 ⚠
pyruvate kinase
— Both
LbrM.26.2630 ⚠
6-phosphogluconolactonase
— Both
LbrM.34.4160 ⚠
Protein of unknown function (DUF2009), putati
— Both
LbrM.25.1580 ⚠
hypothetical protein, conserved
— Both
LbrM.34.0070 ⚠
pyruvate kinase, putative (fragment)
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.