LbrM.11.0730

hypothetical protein, conserved
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_156980 OG7: OG7_0050890 62 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 62 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.21.1130 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.20.5290
DNAj-like protein
— Both
LbrM.07.0990
Domain of unknown function (DUF3437), putativ
— Both
LbrM.11.0720
Short C-terminal domain/PUB domain containing
— Both
LbrM.08.0470
WD domain, G-beta repeat, putative
— Both
LbrM.35.6760 ⚠
protein transport protein Sec23-like protein
— OG7
LbrM.35.3220 ⚠
ATP-dependent RNA helicase, putative
— OG7
LbrM.06.0920 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.2170 ⚠
TLD, putative
— OG7
LbrM.15.0340 ⚠
Ecotin-like protein
— OG7
LbrM.27.1750 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
LbrM.34.3160 ⚠
replication factor C, subunit 3, putative
— OG7
LbrM.34.5330 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.32.0820 ⚠
Outer row dynein-assembly protein 7
— OG7
LbrM.17.1250 ⚠
WW domain containing protein, putative
— OG7
LbrM.28.2700 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
LbrM.13.0440
hypothetical protein, conserved
— Both
LbrM.17.0530 ⚠
ATPase family associated with various cellula
— OG7
LbrM.07.0290 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LbrM.30.2590 ⚠
replication factor C, subunit 2, putative
— OG7
LbrM.30.1210 ⚠
WW domain containing protein, putative
— OG7
LbrM.35.5130 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.7070 ⚠
replication factor C subunit 3, putative
— OG7
LbrM.30.0540 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LbrM.20.5250 ⚠
hypothetical protein, conserved
— OG7
LbrM.19.1750 ⚠
eukaryotic translation initiation factor-like
— OG7
LbrM.29.0610 ⚠
hypothetical protein, conserved
— OG7
LbrM.27.0660 ⚠
replication factor C, subunit 4, putative
— OG7
LbrM.15.0540 ⚠
ecotin, putative
— OG7
LbrM.28.2590 ⚠
WW domain containing protein, putative
— OG7
LbrM.30.1030 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.30.0530 ⚠
Eukaryotic translation initiation factor 4E-4
— Both
LbrM.03.0410 ⚠
TLD domain protein, conserved
— Both
LbrM.09.1150
hypothetical protein, conserved
— Both
LbrM.03.0590 ⚠
DEAD/DEAH box helicase, putative
— Both
LbrM.06.0350
glutamine synthetase, putative
— Both
LbrM.20.1840 ⚠
asparaginyl-tRNA synthetase, putative
— Both
LbrM.15.0550 ⚠
ecotin, putative
— Both
LbrM.34.4770
BRCA1 C Terminus (BRCT) domain containing pro
— Both
LbrM.19.1320
phenylalanyl-tRNA synthetase, putative
— Both
LbrM.15.0530
hypothetical protein, conserved
— Both
LbrM.29.2330
aspartyl aminopeptidase, putative
— Both
LbrM.33.3020
translation initiation factor IF-2, putative
— Both
LbrM.16.1170 ⚠
WW domain containing protein, putative
— Both
LbrM.34.3140 ⚠
cystathione gamma lyase, putative
— Both
LbrM.31.1020
ras-like small GTPases, putative
— OG6
LbrM.23.0600
5'-3' exoribonuclease C, putative
— Both
LbrM.10.0330 ⚠
protein transport protein SEC23, putative
— Both
LbrM.33.2730
Flagellum attachment zone protein 12
— Both
LbrM.24.2100
tubulin folding cofactor D, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.