LbrM.31.1020

ras-like small GTPases, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_478841 OG7: OG7_0000131 60 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 60 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.34.2670
hypothetical protein, conserved
— OG6
LbrM.11.0730
hypothetical protein, conserved
— OG6
LbrM.19.1320
phenylalanyl-tRNA synthetase, putative
— OG6
LbrM.18.1310
bifunctional aminoacyl-tRNA synthetase, putat
— OG6
LbrM.20.1840
asparaginyl-tRNA synthetase, putative
— OG6
LbrM.35.5170
hypothetical protein, conserved
— OG6
LbrM.32.1190
HECT-domain (ubiquitin-transferase), putative
— OG6
LbrM.33.3280
hypothetical protein, unknown function
— OG6
LbrM.34.3110
RNA-binding protein, putative
— OG6
LbrM.34.0910
hypothetical protein, conserved
— OG6
LbrM.34.4770
BRCA1 C Terminus (BRCT) domain containing pro
— OG6
LbrM.20.2310
hypothetical protein, conserved
— OG6
LbrM.33.3020
translation initiation factor IF-2, putative
— OG6
LbrM.33.2550
glycosyl hydrolase-like protein
— OG6
LbrM.33.2730
Flagellum attachment zone protein 12
— OG6
LbrM.23.0600
5'-3' exoribonuclease C, putative
— OG6
LbrM.33.0400
DNA mismatch repair protein MSH2, putative
— OG6
LbrM.33.2150
hypothetical protein, conserved
— OG6
LbrM.32.1140
hypothetical protein, conserved
— OG6
LbrM.33.2190
ribosome assembly protein RRB1, putative
— OG6
LbrM.07.0990
Domain of unknown function (DUF3437), putativ
— OG6
LbrM.11.0720
Short C-terminal domain/PUB domain containing
— OG6
LbrM.22.0060
transcription factor-like protein
— OG6
LbrM.11.0690
hypothetical protein, conserved
— OG6
LbrM.19.1330
hypothetical protein, unknown function
— OG6
LbrM.12.0530
WW domain containing protein, putative
— OG6
LbrM.08.0470
WD domain, G-beta repeat, putative
— OG6
LbrM.28.2080
p21-C-terminal region-binding protein, putati
— OG6
LbrM.26.2250
hypothetical protein, conserved
— OG6
LbrM.30.0830
heat shock protein grpe, co-chaperone, GrpE,
— OG6
LbrM.16.1170
WW domain containing protein, putative
— OG6
LbrM.18.0610
hypothetical protein, conserved
— OG6
LbrM.13.0440
hypothetical protein, conserved
— OG6
LbrM.08.0230
ubiquitin-activating enzyme-like protein (fra
— OG6
LbrM.22.0580
guide RNA associated protein, GAP2, putative
— OG6
LbrM.21.1070
hypothetical protein, conserved
— OG6
LbrM.10.0330
protein transport protein SEC23, putative
— OG6
LbrM.12.0270
cysteinyl-tRNA synthetase, putative
— OG6
LbrM.26.1490
farnesyltransferase beta subunit
— OG6
LbrM.31.0360
ATP-dependent RNA helicase, putative
— OG6
LbrM.24.2100
tubulin folding cofactor D, putative
— OG6
LbrM.15.0550
ecotin, putative
— OG6
LbrM.03.0410
TLD domain protein, conserved
— OG6
LbrM.30.0640
hypothetical protein, conserved
— OG6
LbrM.26.1240
hypothetical protein, conserved
— OG6
LbrM.15.0530
hypothetical protein, conserved
— OG6
LbrM.18.1380
hypothetical protein, conserved
— OG6
LbrM.26.1200
hypothetical protein, conserved
— OG6
LbrM.30.1030
ubiquitin-protein ligase, putative
— OG6
LbrM.29.2330
aspartyl aminopeptidase, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.