LbrM.19.0470

metallo-peptidase, Clan MG, Family M24
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101895 OG7: OG7_0006554 86 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 86 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.29.2440 ⚠
60S ribosomal protein L13, putative
— OG7
LbrM.20.3550 ⚠
target of rapamycin kinase 3, putative
— OG7
LbrM.32.3420 ⚠
ribosomal protein L3, putative
— OG7
LbrM.30.3380 ⚠
60S ribosomal protein L9, putative
— OG7
LbrM.20.3990 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LbrM.13.0510 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LbrM.19.0180 ⚠
hypothetical protein, conserved
— OG7
LbrM.07.0560 ⚠
60S ribosomal protein L7a, putative
— OG7
LbrM.10.0120 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LbrM.20.5280 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LbrM.28.1500 ⚠
hypothetical protein, conserved
— OG7
LbrM.04.0950 ⚠
60S ribosomal protein L10, putative
— OG7
LbrM.21.1950 ⚠
mitochondrial structure specific endonuclease
— OG7
LbrM.02.0130 ⚠
phosphatidylinositol kinase related protein,
— OG7
LbrM.29.1190 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LbrM.35.6620 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LbrM.35.6120 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.4810 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LbrM.34.3110 ⚠
RNA-binding protein, putative
— OG7
LbrM.26.1390 ⚠
GTP-binding protein-like protein, guanine nuc
— OG7
LbrM.26.0160 ⚠
60S ribosomal protein L7, putative
— OG7
LbrM.34.0940 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
LbrM.32.1620 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LbrM.15.0540 ⚠
ecotin, putative
— OG7
LbrM.15.0340 ⚠
Ecotin-like protein
— OG7
LbrM.22.1510 ⚠
ser/thr protein phosphatase, putative
— OG7
LbrM.35.5590 ⚠
hypothetical protein, conserved
— OG7
LbrM.32.3410 ⚠
ribosomal protein L3, putative (fragment)
— OG7
LbrM.05.0470 ⚠
GTPase, putative
— OG7
LbrM.04.0740 ⚠
60S ribosomal protein L10, putative
— OG7
LbrM.07.0710 ⚠
eukaryotic translation initiation factor 3 su
— OG7
LbrM.15.0210 ⚠
60S ribosomal protein L13a, putative
— OG7
LbrM.34.4940 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LbrM.05.0200 ⚠
50S ribosome-binding GTPase, putative
— OG7
LbrM.18.0250 ⚠
60S ribosomal protein L7, putative
— OG7
LbrM.29.0530 ⚠
hypothetical protein, conserved
— OG7
LbrM.32.0060 ⚠
nuclear segregation protein, putative
— OG7
LbrM.29.2430 ⚠
60S ribosomal protein L13, putative
— OG7
LbrM.33.2680 ⚠
ras-like small GTPases, putative
— OG7
LbrM.34.5160 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.0830 ⚠
60S ribosomal protein L13a, putative
— OG7
LbrM.21.1280 ⚠
60S ribosomal protein L9, putative
— OG7
LbrM.25.1360 ⚠
hypothetical protein, conserved
— OG7
LbrM.07.0190 ⚠
protein phosphatase 2A, regulatory subunit B,
— Both
LbrM.06.0420 ⚠
60S ribosomal protein L19, putative
— OG7
LbrM.06.0390 ⚠
60S ribosomal protein L19, putative
— OG7
LbrM.06.1160
Nuclear Dbf2-related kinase
— OG6
LbrM.35.6930 ⚠
hypothetical protein, conserved, y113g7b.23 p
— Both
LbrM.21.1700 ⚠
ATP-dependent RNA helicase SUB2, putative
— Both
LbrM.33.2790 ⚠
UDP-N-acetylglucosamine pyrophosphorylase, pu
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.