LbrM.06.1160

Nuclear Dbf2-related kinase
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_100850 OG7: OG7_0000103 24 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 24 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.13.0520
kinesin, putative
— OG6
LbrM.35.4640
ATP-dependent DEAD/H RNA helicase, putative
— OG6
LbrM.25.1250
NPL4 family, putative
— OG6
LbrM.32.1860 ⚠
protein phosphatase 2C, putative
— OG6
LbrM.17.0060
hypothetical protein, conserved
— OG6
LbrM.30.0990 ⚠
protein phosphatase 2C, putative (fragment)
— OG6
LbrM.35.0620 ⚠
protein phosphatase 2C-like protein
— OG6
LbrM.09.0560
hypothetical protein, unknown function
— OG6
LbrM.28.1870
hypothetical protein, conserved (fragment)
— OG6
LbrM.23.1160
HIT domain containing protein, putative
— OG6
LbrM.35.2380
hypothetical protein, conserved
— OG6
LbrM.09.0780
hypothetical protein, conserved
— OG6
LbrM.06.1050
deoxyribose-phosphate aldolase, putative
— OG6
LbrM.35.4810
PSP1 C-terminal conserved region, putative
— OG6
LbrM.19.0470
metallo-peptidase, Clan MG, Family M24
— OG6
LbrM.27.2510 ⚠
protein phosphatase-like protein
— OG6
LbrM.09.0290
hypothetical protein, conserved
— OG6
LbrM.27.2780 ⚠
metallo-peptidase, Clan MA(E), Family M3
— OG6
LbrM.02.0670 ⚠
peptidyl dipeptidase, putative, metallo-pepti
— OG6
LbrM.27.1640 ⚠
metallo-peptidase, Clan MA(E), Family M3, pep
— OG6
LbrM.27.2760 ⚠
metallo-peptidase, Clan MA(E), Family M3, pep
— OG6
LbrM.26.1590 ⚠
metallo-peptidase, Clan MA(E), Family M3, thi
— OG6
LbrM.27.1650 ⚠
peptidyl dipeptidase, putative, metallo-pepti
— OG6
LbrM.04.0630
spermidine synthase, putative
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.