LbrM.35.2380

hypothetical protein, conserved
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_106165 OG7: OG7_0009984 72 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 72 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.06.1160
Nuclear Dbf2-related kinase
— OG6
LbrM.10.0120 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LbrM.29.1190 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LbrM.32.1720 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LbrM.33.3240 ⚠
hypothetical protein, conserved
— OG7
LbrM.24.0510
hypothetical protein, conserved
— Both
LbrM.26.1750
hypothetical protein, conserved
— Both
LbrM.23.1160
HIT domain containing protein, putative
— Both
LbrM.28.1870
hypothetical protein, conserved (fragment)
— Both
LbrM.13.0510 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LbrM.25.1250
NPL4 family, putative
— Both
LbrM.13.1340
hypothetical protein, conserved
— Both
LbrM.19.0180 ⚠
hypothetical protein, conserved
— Both
LbrM.28.1500 ⚠
hypothetical protein, conserved
— Both
LbrM.34.0940 ⚠
cell cycle sequence binding phosphoprotein (R
— Both
LbrM.09.0780
hypothetical protein, conserved
— Both
LbrM.11.0810
inositol-1,4,5-trisphosphate (IP3) 5-phosphat
— Both
LbrM.27.0700
Domain of unknown function (DUF4470)/Domain o
— Both
LbrM.35.1910 ⚠
hypothetical protein, conserved
— OG7
LbrM.25.2430 ⚠
casein kinase I, putative
— OG7
LbrM.27.1900 ⚠
casein kinase I-like protein
— OG7
LbrM.34.0990 ⚠
casein kinase I, putative
— OG7
LbrM.30.3520 ⚠
casein kinase 1 isoform 2, putative
— OG7
LbrM.20.2600 ⚠
protein kinase, putative
— OG7
LbrM.04.1230 ⚠
casein kinase I, putative
— OG7
LbrM.17.0240
hypothetical protein, conserved
— OG7
LbrM.04.1100
hypothetical protein, conserved
— OG7
LbrM.34.5280
Dynein heavy chain and region D6 of dynein mo
— Both
LbrM.23.0130 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LbrM.23.1810 ⚠
neutral sphingomyelinase activation associate
— OG7
LbrM.23.1900 ⚠
ATP-dependent RNA Helicase
— OG7
LbrM.35.6390 ⚠
rab-like GTPase activating protein, putative
— OG7
LbrM.26.0120 ⚠
adenine phosphoribosyltransferase
— OG7
LbrM.30.2790 ⚠
chaperonin HSP60/CNP60, putative
— OG7
LbrM.34.4940 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LbrM.25.1360 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.4810 ⚠
PSP1 C-terminal conserved region, putative
— Both
LbrM.01.0500
alpha/beta-hydrolase-like protein
— Both
LbrM.01.0090
hypothetical protein, conserved
— Both
LbrM.30.2560
RNA-binding protein, putative
— OG6
LbrM.30.3160
Tumour suppressor, Mitostatin, putative
— Both
LbrM.35.4640 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— Both
LbrM.35.6380 ⚠
disgorgin, putative
— Both
LbrM.35.6470
hypothetical protein, conserved
— Both
LbrM.35.3890
NUDIX hydrolase 3, putative
— Both
LbrM.20.5150 ⚠
1,2-Dihydroxy-3-keto-5-methylthiopentene diox
— Both
LbrM.09.0930
ras family protein-like protein
— OG6
LbrM.26.1020
hypothetical protein, conserved
— Both
LbrM.35.2240 ⚠
chaperonin HSP60, mitochondrial precursor
— Both
LbrM.32.2030 ⚠
Chaperonin HSP60, mitochondrial
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.